THE SIGNIFICANCE OF ALK REARRANGEMENT IN SELECTED ADVANCED NON-SMALL CELL LUNG CANCER: ALK EXPRESSION PROVIDES INSIGHTS INTO ALK TARGET THERAPY

被引:0
|
作者
Zhang, Ningning [1 ,2 ]
Shi, Yuankai [1 ,2 ]
Ma, Li [1 ,2 ]
Hao, Xuezhi [1 ,2 ]
Lin, Dongmei [2 ,3 ]
Han, Xiaohong [1 ,2 ]
Liu, Yutao [1 ,2 ]
Wang, Lin [1 ,2 ]
Yuan, Zheng [2 ,3 ]
Yang, Sheng [1 ,2 ]
机构
[1] Chinese Acad Med Sci, Canc Inst Hosp, Beijing Key Lab Clin Study Anticanc Mol Targeted, Beijing, Peoples R China
[2] Peking Union Med Coll, Beijing, Peoples R China
[3] Chinese Acad Med Sci, Canc Inst Hosp, Dept Pathol, Beijing, Peoples R China
关键词
Alk rearrangement; non-small cell lung cancer; ALK expression; Crizotinib;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P1.11-038
引用
收藏
页码:S612 / S612
页数:1
相关论文
共 50 条
  • [41] Clinical and computed tomography characteristics of non-small cell lung cancer with ALK gene rearrangement: Comparison with EGFR mutation and ALK/EGFR-negative lung cancer
    Mori, Mio
    Hayashi, Hideyuki
    Fukuda, Minoru
    Honda, Sumihisa
    Kitazaki, Takeshi
    Shigematsu, Kazuto
    Matsuyama, Naohiro
    Otsubo, Mayumi
    Nagayasu, Takeshi
    Hashisako, Mikiko
    Tabata, Kazuhiro
    Uetani, Masataka
    Ashizawa, Kazuto
    THORACIC CANCER, 2019, 10 (04) : 872 - 879
  • [42] Economic analysis of ALK testing and crizotinib therapy for advanced non-small-cell lung cancer
    Lu, Shun
    Zhang, Jie
    Ye, Ming
    Wang, Baoai
    Wu, Bin
    PHARMACOGENOMICS, 2016, 17 (09) : 985 - 994
  • [43] Treating ALK-positive non-small cell lung cancer
    Ziogas, Dimitrios C.
    Tsiara, Anna
    Tsironis, Georgios
    Lykka, Maria
    Liontos, Michalis
    Bamias, Aristotelis
    Dimopoulos, Meletios-Athanasios
    ANNALS OF TRANSLATIONAL MEDICINE, 2018, 6 (08)
  • [44] Is alectinib the new first line therapy in ALK-rearranged advanced non-small cell lung cancer?
    van der Wekken, Anthonie J.
    Kok, Klaas
    Groen, Harry J. M.
    JOURNAL OF THORACIC DISEASE, 2018, 10 : S2130 - S2132
  • [45] Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations
    Lou, Na-Na
    Zhang, Xu-Chao
    Chen, Hua-Jun
    Zhou, Qing
    Yan, Li-Xu
    Xie, Zhi
    Su, Jian
    Chen, Zhi-Hong
    Tu, Hai-Yan
    Yan, Hong-Hong
    Wang, Zhen
    Xu, Chong-Rui
    Jiang, Ben-Yuan
    Wang, Bin-Chao
    Bai, Xiao-Yan
    Zhong, Wen-Zhao
    Wu, Yi-Long
    Yang, Jin-Ji
    ONCOTARGET, 2016, 7 (40) : 65185 - 65195
  • [46] Clinical impact of sequential treatment with ALK-TKIs in patients with advanced ALK-positive non-small cell lung cancer: Results of a multicenter analysis
    Chiari, Rita
    Metro, Giulio
    Iacono, Daniela
    Bellezza, Guido
    Rebonato, Alberto
    Dubini, Alessandra
    Sperduti, Isabella
    Bennati, Chiara
    Paglialunga, Luca
    Burgio, Marco Angelo
    Baglivo, Sara
    Giusti, Raffaele
    Minotti, Vincenzo
    Delmonte, Angelo
    Crino, Lucio
    LUNG CANCER, 2015, 90 (02) : 255 - 260
  • [47] Detection of ALK expression in non-small-cell lung cancer with ALK gene rearrangements - comparison of multiple immunohistochemical methods
    Zwaenepoel, Karen
    Van Dongen, Amber
    Lambin, Suzan
    Weyn, Christine
    Pauwels, Patrick
    HISTOPATHOLOGY, 2014, 65 (04) : 539 - 548
  • [48] Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): Results of a multi-centre ALK-testing
    Laffert, Maximilian V.
    Warth, Arne
    Penzel, Roland
    Schirmacher, Peter
    Jonigk, Danny
    Kreipe, Hans
    Schildhaus, Hans-Ulrich
    Merkelbach-Bruse, Sabine
    Buettner, Reinhard
    Reu, Simone
    Kerler, Rosi
    Jung, Andreas
    Kirchner, Thomas
    Woelfel, Cornelius
    Petersen, Iver
    Rodriguez, Regulo
    Jochum, Wolfram
    Bartsch, Holger
    Fisseler-Eckhoff, Annette
    Berg, Erika
    Lenze, Dido
    Dietel, Manfred
    Hummel, Michael
    LUNG CANCER, 2013, 81 (02) : 200 - 206
  • [49] Detection of Anaplastic Lymphoma Kinase (ALK) Gene Rearrangement in Non-Small Cell Lung Cancer and Related Issues in ALK Inhibitor TherapyA Literature Review
    Eunhee S. Yi
    Jin-Haeng Chung
    Kimary Kulig
    Keith M. Kerr
    Molecular Diagnosis & Therapy, 2012, 16 : 143 - 150
  • [50] Mechanisms of suppression of cell growth by dual inhibition of ALK and MEK in ALK-positive non-small cell lung cancer
    Shrestha, N.
    Nimick, M.
    Dass, P.
    Rosengren, R. J.
    Ashton, J. C.
    SCIENTIFIC REPORTS, 2019, 9 (1)