Stem Cells-A Source of Adult Red Blood Cells for Transfusion Purposes: Present and Future

被引：20
|
作者：
Douay, Luc [1 ,2 ,3 ]
Lapillonne, Helene [1 ,2 ,3 ]
Turhan, Ali G. [4 ]
机构：
[1] Hop Armand Trousseau, AP HP, Serv Hematol Biol, F-75012 Paris, France
[2] INSERM, UMR S 893, F-75005 Paris, France
[3] Univ Paris 06, UMR S 893, F-75005 Paris, France
[4] Univ Poitiers, UPRES EA 3805, Div Lab Hematol & Oncol, F-86021 Poitiers, France
来源：
CRITICAL CARE CLINICS | 2009年 / 25卷 / 02期
关键词：
Red blood cell; Transfusion; Enucleation; Hemoglobin; Hematopoietic stem cells; ES cells; IPS; EX-VIVO EXPANSION; HEMATOPOIETIC PROGENITORS; DIFFERENTIATION CULTURES; DEFINED FACTORS; CORD BLOOD; FIBROBLASTS; MARROW; GLOBIN; STROMA; PROLIFERATION;
D O I：
10.1016/j.ccc.2008.12.008
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
We have sufficient knowledge of the biology of hematopoietic stem cells to hope that we might generate human red blood cells in the laboratory. It may soon be possible to produce enough to transfuse "cultured" red blood cells to manufacture human red blood cells from hematopoietic stem cells for transfusion purposes. This article describes progress and the challenges that remain in the search for in vitro generated red blood cells that can be efficiently manufactured in high volumes and given to any recipient.
引用
收藏
页码：383 / +
页数：17
相关论文
共 50 条
  • [41] Cryopreserved red blood cells are superior to standard liquid red blood cells
    Hampton, David A.
    Wiles, Connor
    Fabricant, Loic J.
    Kiraly, Laszlo
    Differding, Jerome
    Underwood, Samantha
    Le, Dinh
    Watters, Jennifer
    Schreiber, Martin A.
    JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2014, 77 (01): : 20 - 26
  • [42] What is the future for cord blood stem cells?
    de Wynter, EA
    CYTOTECHNOLOGY, 2003, 41 (2-3) : 133 - 138
  • [43] What is the future for cord blood stem cells?
    E. A. de Wynter
    Cytotechnology, 2003, 41 : 133 - 138
  • [44] Transfusion in premature infants impairs production and/or release of red blood cells, white blood cells and platelets
    Frey, B
    JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 2002, 38 (03) : 265 - 267
  • [45] Generation of red blood cells from induced pluripotent stem cells
    Gunawardena, Naomi
    Chou, Stella T.
    CURRENT OPINION IN HEMATOLOGY, 2024, 31 (03) : 115 - 121
  • [46] A niche for axial stem cells-A cellular perspective in amniotes
    Solovieva, Tatiana
    Wilson, Valerie
    Stern, Claudio D.
    DEVELOPMENTAL BIOLOGY, 2022, 490 : 13 - 21
  • [47] Generation of red blood cells from stem cells: Achievements, opportunities and perspectives for malaria research
    Satchwell, Timothy J.
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 12
  • [48] Cultured Red Blood Cells: A New Advance in Stem Cell Engineering
    Blume, Karl G.
    PROGRESS AND CHALLENGES IN TRANSFUSION MEDICINE, HEMOSTASIS AND HEMOTHERAPY: STATE OF THE ART 2008, 2008, : 15 - 23
  • [49] Cultured Red Blood Cells: A New Advance in Stem Cell Engineering
    Douay, Luc
    PROGRESS AND CHALLENGES IN TRANSFUSION MEDICINE, HEMOSTASIS AND HEMOTHERAPY: STATE OF THE ART 2008, 2008, : 151 - 161
  • [50] Ex-vivo expansion of red blood cells: How real for transfusion in humans?
    Migliaccio, Anna Rita
    Masselli, Elena
    Varricchio, Lilian
    Whitsett, Carolyn
    BLOOD REVIEWS, 2012, 26 (02) : 81 - 95
12345