Metal-catalyzed regioselective oxy-functionalization of internal alkynes: An entry into ketones, acetals, and spiroketals

被引：210

作者：

Liu, Bo ^{[1
]}

De Brabander, Jef K. ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr Dallas, Dept Biochem, Dallas, TX 75390 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 21期

关键词：

D O I：

10.1021/ol0619819

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Platinum(II) and an unusual cationic gold( I) complex were identified as mild catalysts for the room temperature cycloisomerization or tandem hydroalkoxylation/acetal formation of unactivated internal alkynols. Under the appropriate conditions, 5-endo, 5-exo, 6-endo, and 6-exo cycloisomerization modes are all available.

引用

页码：4907 / 4910

页数：4

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