Structured white-light illumination for diagnostic investigations

被引：0
|
作者：
Schau, P. [1 ]
Brandes, A. [2 ]
Frenner, K. [1 ]
Kienle, A. [2 ]
Osten, W. [1 ]
机构：
[1] Univ Stuttgart, Inst Tech Opt, Pfaffenwaldring 9, D-70569 Stuttgart, Germany
[2] Univ Ulm, Inst Lasertech Medizin & Messtech, D-89081 Ulm, Germany
来源：
OPTICAL METHODS FOR INSPECTION, CHARACTERIZATION, AND IMAGING OF BIOMATERIALS | 2013年 / 8792卷
关键词：
White light interference; structured illumination; optical systems; depth-sensitive measurement; fluorescence detection; Monte Carlo; radiative transfer; TRANSPORT;
D O I：
10.1117/12.2020624
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
For fluorescence measurements of strongly-scattering samples such as biological tissue but also for technical surfaces, we propose a structured white-light illumination. We present two different approaches for the sample illumination utilizing a white light laser or a white light LED, respectively. We show first simulations of the individual illumination setups and their impact on the scattering within the sample. Furthermore, we investigated the distribution of the fluorescent light that reaches the detection part of the device when excited within a scattering medium, for this purpose we implemented a novel fast-converging algorithm for conditional fluence rate in our Monte Carlo algorithm.
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页数：7
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