A SEROLOGIC SURVEY OF FRANCISELLA TULARENSIS EXPOSURE IN WILDLIFE ON THE ARCTIC COASTAL PLAIN OF ALASKA, USA

被引:0
作者
Smith, Matthew M. [1 ]
Van Hemert, Caroline [1 ]
Atwood, Todd C. [1 ]
Sinnett, David R. [2 ]
Hupp, Jerry W. [1 ]
Meixell, Brandt W. [1 ,3 ]
Gustine, Dave D. [1 ,4 ]
Adams, Layne G. [1 ]
Ramey, Andrew M. [1 ]
机构
[1] US Geol Survey, Alaska Sci Ctr, 4210 Univ Dr, Anchorage, AK 99508 USA
[2] APHIS Wildlife Serv, USDA, 9001 E Frontage Rd, Palmer, AK 99645 USA
[3] US Forest Serv, Chugach Natl Forest, POB 280, Cordova, AK 99574 USA
[4] US Fish & Wildlife Serv, Marine Mammals Management Polar Bears, 1011 E Tudor Rd, Anchorage, AK 99503 USA
关键词
Alaska; Arctic Coastal Plain; bacteria; Francisella tularensis; serology; tularemia; wildlife; zoonoses; BEARS URSUS-ARCTOS; LEMMING POPULATIONS; FOX; VARIABILITY; TULAREMIA; PATHOGENS; DYNAMICS; ECOLOGY; WOLVES; AGENTS;
D O I
10.7589/JWD-D-51-00162
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Tularemia is an infectious zoonotic disease caused by one of several subspecies of Francisella tularensis bacteria. Infections by F. tularensis are common throughout the northern hemisphere and have been detected in more than 250 wildlife species. In Alaska, US, where the pathogen was first identified in 1938, studies have identified F. tularensis antibodies in a diverse suite of taxa, including insects, birds, and mammals. However, few such investigations have been conducted recently and knowledge about the current distribution and disease ecology of F. tularensis is limited, particularly in Arctic Alaska, an area undergoing rapid environmental changes from climate warming. To help address these information gaps and provide insights about patterns of exposure among wildlife, we assessed the seroprevalence of P. tularensis antibodies in mammals and tundra-nesting geese from the Arctic Coastal Plain of Alaska, 2014-17. With a commercially available slide agglutination test, we detected antibodies in 14.7% of all individuals sampled (n=722), with titers ranging from 1:20 to 1:320. We detected significant differences in seroprevalence between family groups, with Canidae (foxes, Vulpes spp.) and Sciuridae (Arctic ground squirrel, Spermophilus parryii) having the highest seroprevalence at 21.5% and 33.3%, respectively. Mean seroprevalence for Ursidae (polar bears, Ursus maritimus) was 13.3%, whereas Cervidae (caribou, Rangifer tarandus) had comparatively low seroprevalence at 6.5%. Antibodies were detected in all Anatidae species sampled, with Black Brant (Branta berniela nigricans) having the highest seroprevalence at 13.6%. The detection of F. tularensis antibodies across multiple taxa from the Arctic Coastal Plain and its nearshore marine region provides evidence of exposure to this pathogen throughout the region and highlights the need for renewed surveillance in Alaska.
引用
收藏
页码:746 / 755
页数:10
相关论文
共 51 条
[21]   Growth of Black Brant and Lesser Snow Goose Goslings in Northern Alaska [J].
Hupp, Jerry W. ;
Ward, David H. ;
Hogrefe, Kyle R. ;
Sedinger, James S. ;
Martin, Philip D. ;
Stickney, Alice A. ;
Obritschkewitsch, Tim .
JOURNAL OF WILDLIFE MANAGEMENT, 2017, 81 (05) :846-857
[22]   Terrestrial predation by polar bears: not just a wild goose chase [J].
Iles, D. T. ;
Peterson, S. L. ;
Gormezano, L. J. ;
Koons, D. N. ;
Rockwell, R. F. .
POLAR BIOLOGY, 2013, 36 (09) :1373-1379
[23]   Molecular epidemiology, evolution, and ecology of Francisella [J].
Keim, Paul ;
Johansson, Anders ;
Wagner, David M. .
FRANCISELLA TULARENSIS: BIOLOGY, PATHOGENICITY, EPIDEMIOLOGY, AND BIODEFENSE, 2007, 1105 :30-66
[24]   Further observations on a plague like disease of rodents with a preliminary note on the causative agent, bacterium tularense [J].
McCoy, G ;
Chapin, CW .
JOURNAL OF INFECTIOUS DISEASES, 1912, 10 (01) :61-72
[25]  
McCoy GW., 1911, Publ Health Bull, V43, P53
[26]   Interrater reliability: the kappa statistic [J].
McHugh, Mary L. .
BIOCHEMIA MEDICA, 2012, 22 (03) :276-282
[27]  
Morner T., 1992, Revue Scientifique et Technique Office International des Epizooties, V11, P1123
[28]  
MORNER T, 1988, J WILDLIFE DIS, V24, P422
[29]   Effects of weather and parasitic insects on behavior and group dynamics of caribou of the Delta Herd, Alaska [J].
Morschel, FH ;
Klein, DR .
CANADIAN JOURNAL OF ZOOLOGY-REVUE CANADIENNE DE ZOOLOGIE, 1997, 75 (10) :1659-1670
[30]  
Morton JK, 1989, THESIS U ALASKA