Norsampsones A-D, Four New Decarbonyl Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii

被引：59

作者：

Tian, Wen-Jing ^{[1
]}

Yu, Yang ^{[2
]}

Yao, Xiao-Jun ^{[3
]}

Chen, Hai-Feng ^{[4
]}

Dai, Yi ^{[2
]}

Zhang, Xiao-Kun ^{[4
]}

Yao, Xin-Sheng ^{[1
,2
]}

机构：

[1] Shenyang Pharmaceut Univ, Coll Tradit Chinese Mat Med, Shenyang 110016, Peoples R China

[2] Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China

[3] Macau Univ Sci & Technol, Macau Inst Appl Res Med & Hlth, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China

[4] Xiamen Univ, Inst Biomed Res, Xiamen 361005, Peoples R China

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 13期

关键词：

POLYISOPRENYLATED BENZOYLPHLOROGLUCINOL DERIVATIVES; BENZOPHENONE DERIVATIVES; UNIQUE FAMILY; COHAERENS;

D O I：

10.1021/ol501333k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Norsampsones A-D (1-4), four new decarbonyl polycyclic polyprenylated acylphloroglucinols, together with a new biogenetically related compound hypersampsone M (5), were isolated from the aerial parts of Hypericum sampsonii. Norsampsones A D featured an unprecedented carbon skeleton with the loss of C-2 carbonyl in the phloroglucinol ring. All structures were determined by extensive NMR spectroscopic methods, ECD calculation, and single-crystal X-ray diffraction.

引用

页码：3448 / 3451

页数：4

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