Total thyroidectomy versus thyroid lobectomy for papillary thyroid cancer: Comparative analysis after propensity score matching: A multicenter study

被引：62

作者：

Kuba, Sayaka ^{[1
]}

Yamanouchi, Kosho ^{[1
]}

Hayashida, Naomi ^{[1
]}

Maeda, Shigeto ^{[2
]}

Adachi, Toshiyuki ^{[1
]}

Sakimura, Chika ^{[1
]}

Kawakami, Fusako ^{[1
]}

Yano, Hiroshi ^{[3
]}

Matsumoto, Megumi ^{[3
]}

Otsubo, Ryota ^{[3
]}

Sato, Shuntaro ^{[4
]}

Fujioka, Hikaru ^{[2
]}

Kuroki, Tamotsu ^{[1
]}

Nagayasu, Takeshi ^{[3
]}

Eguchi, Susumu ^{[1
]}

机构：

[1] Nagasaki Univ, Dept Surg, Grad Sch Biomed Sci, 1-7-1 Sakamoto Machi, Nagasaki 8528501, Japan

[2] Nagasaki Med Ctr, Natl Hosp, Dept Surg, Nagasaki, Japan

[3] Nagasaki Univ, Dept Surg Oncol, Grad Sch Biomed Sci, Nagasaki, Japan

[4] Nagasaki Univ, Clin Res Ctr, Grad Sch Biomed Sci, Nagasaki, Japan

来源：

INTERNATIONAL JOURNAL OF SURGERY | 2017年 / 38卷

关键词：

Papillary thyroid cancer; Total thyroidectomy; Thyroid lobectomy; Overall survival; Recurrence free survival; Adverse event; CARCINOMA; EXTENT; SURGERY; RISK; CHILDHOOD; SURVIVAL; CHILDREN;

D O I：

10.1016/j.ijsu.2016.09.083

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background: In patients with papillary thyroid carcinoma (PTC), the role of total thyroidectomy (TT) versus that of thyroid lobectomy (TL) has been controversial. Methods: This retrospective study was approved by our institutional review board, and the requirement to obtain informed consent was waived. In total, 173 patients with 1- to 5-cm stage cN0 and cM0 PTC tumors treated by curative surgery from 1994 to 2008 were evaluated. Clinicopathologic features and adverse events were compared between patients who underwent TT and those who underwent TL. After adjustment for differences in baseline clinicopathologic factors using propensity score matching, we compared recurrence-free survival (RFS) and OS. Results: TL was performed in 120 patients and TT in 53 patients. Patients who underwent TT were older; had larger tumors; more frequently had nodal metastasis, multifocal tumors, and extracapsular invasion; and more frequently underwent radioactive iodine ablation than patients who underwent TL. Hypocalcemia requiring medication and recurrent laryngeal nerve paralysis were more frequent in TT than TL. The 10-year RFS and OS of all patients were 93.3% and 96.7%, respectively. There was no significant difference in RFS (90.6% vs 93.0% in TT and TL groups, respectively) or OS (96.2% vs 96.9% in TT and TL groups, respectively) according to the extent of surgical resection after propensity score matching. Conclusion: Equivalent prognoses were observed for patients with 1- to 5-cm stage cN0 and cM0 PTC tumors treated by TL or TT after propensity score matching. Adverse events occurred less frequently in patients who underwent TL than TT. (C) 2016 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

引用

页码：143 / 148

页数：6

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