Triggering Cu-coordination change in Cu(ii)-Ala-His-His by external ligands

被引：16

作者：

Gonzalez, Paulina ^{[1
,2
,3
]}

Bossak-Ahmad, Karolina ^{[4
]}

Vileno, Bertrand ^{[1
,5
]}

Wezynfeld, Nina E. ^{[1
]}

El Khoury, Youssef ^{[6
]}

Hellwig, Petra ^{[2
,6
]}

Hureau, Christelle ^{[2
,3
]}

Bal, Wojciech ^{[4
]}

Faller, Peter ^{[1
,2
]}

机构：

[1] Univ Strasbourg, CNRS, UMR 7177, Inst Chim, 4 Rue Blaise Pascal, F-67000 Strasbourg, France

[2] USIAS, Strasbourg, France

[3] Univ Toulouse, CNRS, LCC, Toulouse, France

[4] Polish Acad Sci, Inst Biochem & Biophys, Pawinskiego 5a, PL-02106 Warsaw, Poland

[5] French EPR Federat Res REseau Natl Rpe InterDisci, Federat IR RPE CNRS 3443, Strasbourg, France

[6] Univ Strasbourg, CNRS, UMR 7140, Lab Bioelectrochim & Spect, 4 Rue Blaise Pascal, F-67000 Strasbourg, France

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 56期

关键词：

XXX-HIS; BINDING; COPPER(II); CU(II); COMPLEXES; PEPTIDES; TRIPEPTIDE; STABILITY; AMINO;

D O I：

10.1039/c9cc03174j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Copper(ii) forms well-known and stable complexes with peptides having histidine at position 2 (Xxx-His) or 3 (Xxx-Zzz-His). Their properties differ considerably due to the histidine positioning. Here we report that in the hybrid motif Xxx-His-His, the Cu(ii)-complexes can be switched between the Xxx-His and the Xxx-Zzz-His coordination modes by addition of external ligands.

引用

收藏

页码：8110 / 8113

页数：4

相关论文

共 27 条

[1] ESR STUDIES OF THE INTERACTION OF COPPER(II)GHK, HISTIDINE, AND EHRLICH CELLS [J].

ANTHOLINE, WE ;

PETERING, DH ;

PICKART, L .

JOURNAL OF INORGANIC BIOCHEMISTRY, 1989, 35 (03) :215-224

[2] Copper [J].

Barceloux, DG .

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1999, 37 (02) :217-230

[3] Measurement of Interpeptidic Cu(II) Exchange Rate Constants by Static Fluorescence Quenching of Tryptophan [J].

Beuning, Cheryle N. ;

Mestre-Voegtle, Beatrice ;

Faller, Peter ;

Hureau, Christelle ;

Crans, Debbie C. .

INORGANIC CHEMISTRY, 2018, 57 (09) :4791-4794

[4] Interactions of α-Factor-1, a Yeast Pheromone, and Its Analogue with Copper(II) Ions and Low-Molecular-Weight Ligands Yield Very Stable Complexes [J].

Bossak, Karolina ;

Mital, Mariusz ;

Poznanski, Jaroslaw ;

Bonna, Arkadiusz ;

Drew, Simon ;

Bal, Wojciech .

INORGANIC CHEMISTRY, 2016, 55 (16) :7829-7831

[5] Oligopeptides Generated by Neprilysin Degradation of β-Amyloid Have the Highest Cu(II) Affinity in the Whole Aβ Family [J].

Bossak-Ahmad, Karolina ;

Mital, Mariusz ;

Plonka, Dawid ;

Drew, Simon C. ;

Bal, Wojciech .

INORGANIC CHEMISTRY, 2019, 58 (01) :932-943

[6]

Casella L., 1990, Biol. Metals, V3, P137

[7] N-Terminal Cu-Binding Motifs (Xxx-Zzz-His, Xxx-His) and Their Derivatives: Chemistry, Biology and Medicinal Applications [J].

Gonzalez, Paulina ;

Bossak, Karolina ;

Stefaniak, Ewelina ;

Hureau, Christelle ;

Raibaut, Laurent ;

Bal, Wojciech ;

Faller, Peter .

CHEMISTRY-A EUROPEAN JOURNAL, 2018, 24 (32) :8029-8041

[8] Cu(II) Binding to the Peptide Ala-His-His, a Chimera of the Canonical Cu(II)-Binding Motifs Xxx-His and Xxx-Zzz-His [J].

Gonzalez, Paulina ;

Vileno, Bertrand ;

Bossak, Karolina ;

El Khoury, Youssef ;

Hellwig, Petra ;

Bal, Wojciech ;

Hureau, Christelle ;

Faller, Peter .

INORGANIC CHEMISTRY, 2017, 56 (24) :14870-14879

[9] Amino terminal Cu(II)- and Ni(II)-binding (ATCUN) motif of proteins and peptides: Metal binding, DNA cleavage, and other properties [J].

Harford, C ;

Sarkar, B .

ACCOUNTS OF CHEMICAL RESEARCH, 1997, 30 (03) :123-130

[10] X-ray and Solution Structures of CuIIGHK and CuIIDAHK Complexes: Influence on Their Redox Properties [J].

Hureau, Christelle ;

Eury, Helene ;

Guillot, Regis ;

Bijani, Christian ;

Sayen, Stephanie ;

Solari, Pier-Lorenzo ;

Guillon, Emmanuel ;

Faller, Peter ;

Dorlet, Pierre .

CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (36) :10151-10160