Tardive dyskinesia: Possible involvement of free radicals and treatment with vitamin E

被引：86
作者：
Elkashef, AM
Wyatt, RJ
机构：
[1] NIDA, Medicat Dev Div, Bethesda, MD 20892 USA
[2] NIDA, Neuropsychiat Branch, NIH, Bethesda, MD 20892 USA
来源：
SCHIZOPHRENIA BULLETIN | 1999年 / 25卷 / 04期
关键词：
tardive dyskinesia; free radicals; neurodegeneration; vitamin E; antioxidants; neuroleptic;
D O I：
10.1093/oxfordjournals.schbul.a033414
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
A decade ago a hypothesis introduced to explain tardive dyskinesia (TD) implicated free radicals generated secondary to neuroleptic treatment. Since then many preclinical and clinical studies have investigated this possibility. These studies suggest that free radicals are probably involved in the pathogenesis of TD and that vitamin E could be efficacious in its treatment.
引用
收藏
页码：731 / 740
页数：10
相关论文
共 50 条
[31]   Pharmacotherapy for the treatment of tardive dyskinesia in schizophrenia patients [J].
Witter, Daniel P. ;
Holbert, Richard C. ;
Suryadevara, Uma .
EXPERT OPINION ON PHARMACOTHERAPY, 2017, 18 (10) :965-972
[32]   CALCIUM-CHANNEL BLOCKERS AND VITAMIN-E FOR TARDIVE-DYSKINESIA IN ADULTS WITH MENTAL-RETARDATION [J].
RICKETTS, RW ;
SINGH, NN ;
ELLIS, CR ;
CHAMBERS, S ;
SINGH, YN ;
CARMANICO, SJ ;
VADNEY, V ;
COOKE, JC .
JOURNAL OF DEVELOPMENTAL AND PHYSICAL DISABILITIES, 1995, 7 (02) :161-174
[33]   Vitamin E supplementation in Alzheimer's disease, Parkinson's disease, tardive dyskinesia, and cataract: Part 2 [J].
Pham, DQ ;
Plakogiannis, R .
ANNALS OF PHARMACOTHERAPY, 2005, 39 (12) :2065-2072
[34]   Pathophysiology, prognosis and treatment of tardive dyskinesia [J].
Takeuchi, Hiroyoshi ;
Mori, Yasuhiro ;
Tsutsumi, Yuichiro .
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY, 2022, 12
[35]   TARDIVE-DYSKINESIA IN NEUROLEPTIC TREATMENT [J].
WETTERLING, T .
NERVENHEILKUNDE, 1994, 13 (05) :212-217
[36]   Botulinum toxin as a treatment for tardive dyskinesia [J].
van Harten, Peter N. ;
Hovestadt, Ad .
MOVEMENT DISORDERS, 2006, 21 (08) :1276-1277
[37]   Valbenazine for the Treatment of Adults with Tardive Dyskinesia [J].
Gupta, Harshit ;
Moity, Alycee R. ;
Jumonville, Allison ;
Kaufman, Sarah ;
Edinoff, Amber N. ;
Kaye, Alan D. .
HEALTH PSYCHOLOGY RESEARCH, 2021, 9 (01)
[38]   Tardive dyskinesia update: treatment and management [J].
Owens, David Cunningham .
BJPSYCH ADVANCES, 2019, 25 (02) :78-89
[39]   Tardive dyskinesia, clozapine, and treatment response [J].
Dalack, GW ;
Becks, L ;
Meador-Woodruff, JH .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1998, 22 (04) :567-573
[40]   Vitamin B6 in treatment of tardive dyskinesia: A preliminary case series study [J].
Lerner, V ;
Kaptsan, A ;
Miodownik, C ;
Kotler, M .
CLINICAL NEUROPHARMACOLOGY, 1999, 22 (04) :241-243
12345