Tardive dyskinesia: Possible involvement of free radicals and treatment with vitamin E

被引：86
作者：
Elkashef, AM
Wyatt, RJ
机构：
[1] NIDA, Medicat Dev Div, Bethesda, MD 20892 USA
[2] NIDA, Neuropsychiat Branch, NIH, Bethesda, MD 20892 USA
来源：
SCHIZOPHRENIA BULLETIN | 1999年 / 25卷 / 04期
关键词：
tardive dyskinesia; free radicals; neurodegeneration; vitamin E; antioxidants; neuroleptic;
D O I：
10.1093/oxfordjournals.schbul.a033414
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
A decade ago a hypothesis introduced to explain tardive dyskinesia (TD) implicated free radicals generated secondary to neuroleptic treatment. Since then many preclinical and clinical studies have investigated this possibility. These studies suggest that free radicals are probably involved in the pathogenesis of TD and that vitamin E could be efficacious in its treatment.
引用
收藏
页码：731 / 740
页数：10
相关论文
共 50 条
[21]   Melatonin for the treatment of tardive dyskinesia [J].
Nelson, LA ;
McGuire, JM ;
Hausafus, SN .
ANNALS OF PHARMACOTHERAPY, 2003, 37 (7-8) :1128-1131
[22]   Treatment Recommendations for Tardive Dyskinesia [J].
Ricciardi, Lucia ;
Pringsheim, Tamara ;
Barnes, Thomas R. E. ;
Martino, Davide ;
Gardner, David ;
Remington, Gary ;
Addington, Donald ;
Morgante, Francesca ;
Poole, Norman ;
Carson, Alan ;
Edwards, Mark .
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2019, 64 (06) :388-399
[23]   Valbenazine for the treatment of tardive dyskinesia [J].
Mueller, Thomas .
EXPERT REVIEW OF NEUROTHERAPEUTICS, 2017, 17 (12) :1135-1144
[24]   Tetrabenazine for the Treatment of Tardive Dyskinesia [J].
Leung, Jonathan G. ;
Breden, Ericka L. .
ANNALS OF PHARMACOTHERAPY, 2011, 45 (04) :525-531
[25]   Lack of effect of vitamin E on serum creatine phosphokinase in patients with long-term tardive dyskinesia [J].
Dorevitch, A ;
Lerner, V ;
Shalfman, M ;
Kalian, M .
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 1997, 12 (03) :171-173
[26]   Treatment of Tardive Dyskinesia with Aripiprazole [J].
Osorio, Ricardo S. ;
Aguera-Ortiz, L. ;
Hurtado de Mendoza, A. ;
Ramos, I. ;
Palomo, T. .
NEUROTOXICITY RESEARCH, 2010, 17 (04) :432-434
[27]   Current treatment of tardive dyskinesia [J].
Margolius, Adam ;
Fernandez, Hubert H. .
PARKINSONISM & RELATED DISORDERS, 2019, 59 :155-160
[28]   Valbenazine for the treatment of tardive dyskinesia [J].
Seeberger, Lauren C. ;
Hauser, Robert A. .
EXPERT OPINION ON PHARMACOTHERAPY, 2017, 18 (12) :1279-1287
[29]   VALBENAZINE FOR THE TREATMENT OF TARDIVE DYSKINESIA [J].
Barquero, N. .
DRUGS OF TODAY, 2016, 52 (12) :665-672
[30]   Apolipoprotein E ε4 and tardive dyskinesia in a Japanese population [J].
Kimura, T ;
Shono, M ;
Yokota, S ;
Ishizuka, K ;
Watanabe, M ;
Takamatsu, J ;
Miyakawa, T .
JOURNAL OF PSYCHIATRIC RESEARCH, 2000, 34 (4-5) :329-332
12345