Tin- and indium-mediated allylation reactions in water:: Highly stereoselective synthesis of β-trifluoromethylated homoallylic alcohols

被引：0

作者：

Loh, TP ^{[1
]}

Li, XR ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 1999卷 / 08期

关键词：

allylation; 1,1,1-trifluoro-4-bromobut-2-ene; aldehydes; tin; indium; water;

D O I：

10.1002/(SICI)1099-0690(199908)1999:8<1893::AID-EJOC1893>3.0.CO;2-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The indium-mediated allylation reaction of aldehydes with 4-bromo-1,1,1-trifluoro-2-butene in water afforded beta-trifluoromethylated homoallylic alcohols in high yields. In most cases, high regio- and excellent diastereoselectivities were obtained.

引用

页码：1893 / 1899

页数：7

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