Effect of Paracetamol, Dexketoprofen Trometamol, Lidocaine Spray, and Paracervical Block Application for Pain Relief during Suction Termination of First-Trimester Pregnancy

被引:9
作者
Acmaz, Gokhan [1 ]
Aksoy, Huseyin [2 ]
Ozoglu, Nil [3 ]
Aksoy, Ulku [1 ]
Albayrak, Evrim [4 ]
机构
[1] Kayseri Educ & Res Hosp Med, Dept Obstet & Gynecol, TR-38210 Kayseri, Turkey
[2] Kayseri Mil Hosp, Dept Obstet & Gynecol, Kayseri, Turkey
[3] Kayseri Educ & Res Hosp Med, Clin Family Planning, TR-38210 Kayseri, Turkey
[4] Erciyes Univ, Sch Med, Dept Midwifery, TR-38210 Kayseri, Turkey
关键词
INTRAVENOUS PARACETAMOL; RANDOMIZED-TRIAL; ABORTION; CURETTAGE; EFFICACY;
D O I
10.1155/2013/869275
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The aim of the study was to investigate the analgesic efficacy of preoperative oral dexketoprofen trometamol, intravenous paracetamol, lidocaine spray, and paracervical block with ultracaine on curettage procedure. A total of 111 subjects with the request of pregnancy termination between 5 and 7 weeks of gestation were included in the study. The first group ( control group) consisted of 20 participants without medication. The second group consisted of 25 participants receiving 2 puffs of lidocaine sprays on cervical mucosa. The third group consisted of 20 participants receiving oral 25 mg dexketoprofen trometamol. The fourth group consisted of 23 participants receiving 1000 mg intravenous paracetamol and the fifth group consisted of 23 participants receiving paracervical block with ultracaine. Paracervical block reduced pain score significantly in both intraoperative and postoperative periods. All analgesic procedures were significantly effective for reducing pain in postoperative period. Paracervical block may be the best method for reducing pain scores in intraoperative and postoperative periods during curettage procedure. All analgesic procedures such as lidocaine, paracetamol, ultracaine, and paracervical block with ultracaine can be used for reducing pain score in postoperative period. This trial is registered with NCT01947205.
引用
收藏
页数:5
相关论文
共 18 条
[1]   Analgesic efficacy of intravenous paracetamol for outpatient fractional curettage: a randomised, controlled trial [J].
Api, O. ;
Unal, O. ;
Ugurel, V. ;
Emeksiz, M. B. ;
Turan, C. .
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2009, 63 (01) :105-111
[2]   Comparison of oral nonsteroidal analgesic and intrauterine local anesthetic for pain relief in uterine fractional curettage: a randomized, double-blind, placebo-controlled trial [J].
Api, Olus ;
Ergen, Bahar ;
Api, Murat ;
Ugurel, Vedat ;
Emeksiz, Muge Balcin ;
Unal, Orhan .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2010, 203 (01) :28.e1-28.e7
[3]  
Arici S, 2009, AGRI, V21, P54
[4]   Acetaminophen: beyond pain and fever-relieving [J].
Blough, Eric R. ;
Wu, Miaozong .
FRONTIERS IN PHARMACOLOGY, 2011, 2
[5]   A TIME AND COST-ANALYSIS OF THE MANAGEMENT OF INCOMPLETE ABORTION WITH MANUAL VACUUM ASPIRATION [J].
BLUMENTHAL, PD ;
REMSBURG, RE .
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 1994, 45 (03) :261-267
[6]  
Cunningham F. G., 2005, WILLIAMS OBSTET, P479
[7]  
Flouvat B, 2004, INT J CLIN PHARM TH, V42, P50
[8]   DEATHS FROM PARACERVICAL ANESTHESIA USED FOR 1ST-TRIMESTER ABORTION, 1972-1975 [J].
GRIMES, DA ;
CATES, W .
NEW ENGLAND JOURNAL OF MEDICINE, 1976, 295 (25) :1397-1399
[9]   Parecoxib sodium demonstrates gastrointestinal safety comparable to placebo in healthy subjects [J].
Harris, SI ;
Stoltz, RR ;
LeComte, D ;
Hubbard, RC .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2004, 38 (07) :575-580
[10]  
Li HWR, 2006, HUM REPROD, V21, P1461, DOI 10.1093/humrep/del023