GREEN SYNTHESIS OF BENZAMIDES IN SOLVENT- AND ACTIVATION-FREE CONDITIONS

被引：9

作者：

Alalla, Affef ^{[1
]}

Merabet-Khelassi, Mounia ^{[1
]}

Aribi-Zouioueche, Louisa ^{[1
]}

Riant, Olivier ^{[2
]}

机构：

[1] Badji Mokhtar Annaba Univ, Ecocompatible Asymmetr Catalysis Lab LCAE, Annaba 23000, Algeria

[2] Catholic Univ Louvain, Inst Condensed Matter & Nanosci Mol Solids & Reac, IMCN, MOST, Louvain La Neuve, Belgium

来源：

SYNTHETIC COMMUNICATIONS | 2014年 / 44卷 / 16期

关键词：

Acetylation; anilines; benzoylation; enol esters; green chemistry; HIGHLY EFFICIENT CATALYST; AMIDE BOND FORMATION; ISOPROPENYL ACETATE; KINETIC RESOLUTION; ACYLATING AGENT; N-ACYLATION; AMINES; ALCOHOLS; LIPASE; BENZOYLATION;

D O I：

10.1080/00397911.2014.898072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, we describe a clean and ecocompatible pathway for both N-benzoylation and N-acetylation of anilines, amines, diamines, and aminoalcohols using three enol esters with good yields. We have improved the use of vinyl benzoate for the direct introduction of a benzamido-moiety under solvent- and activation-free conditions. The recovered amides are easily isolated by crystallization.

引用

页码：2364 / 2376

页数：13

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