Thrombotic risk assessment in APS: the Global APS Score (GAPSS)

被引:20
作者
Sciascia, S. [1 ,2 ]
Bertolaccini, M. L. [1 ]
机构
[1] Kings Coll London, Graham Hughes Lupus Res Lab, Lupus Res Unit, Rayne Inst,Div Womens Hlth, London SE1 7EH, England
[2] Univ Turin, Ctr Ric Immunol Clin & Immunopatol Documentaz & M, I-10124 Turin, Italy
关键词
Antiphospholipid antibodies; pregnancy loss; thrombosis; Hughes syndrome; prothrombin; ANTIPHOSPHOLIPID SYNDROME SCORE; PREDICTION;
D O I
10.1177/0961203314541317
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recently, we developed a risk score for antiphospholipid syndrome (APS) (Global APS Score or GAPSS). This score derived from the combination of independent risk factors for thrombosis and pregnancy loss, taking into account the antiphospholipid antibodies (aPL) profile (criteria and non-criteria aPL), the conventional cardiovascular risk factors, and the autoimmune antibodies profile. We demonstrate that risk profile in APS can be successfully assessed, suggesting that GAPSS can be a potential quantitative marker of APS-related clinical manifestations.
引用
收藏
页码:1286 / 1287
页数:2
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