Primary prevention of diabetes mellitus type 2

被引：0

作者：

Gallwitz, B ^{[1
]}

机构：

[1] Univ Tubingen, Med Klin 4, D-72076 Tubingen, Germany

来源：

INTERNIST | 2004年 / 45卷

关键词：

diabetes prevention; impaired glucose tolerance; metformin; acarbose; life style intervention;

D O I：

10.1007/s00108-004-1214-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The increasing incidence of type 2 diabetes constitutes a considerable individual and socio-economic risk, therefore preventive concepts are urgently needed. Three prospective studies show that a "life-style-intervention" as well as drugs can prevent the development of diabetes as well as cardiovascular complications: The Diabetes Prevention Study (DPS) evaluated,the influence of a "life-style-intervention" The Diabetes Prevention Program (DPP) additionally examined the effect of metformin. In the Stop-NIDDM-Study acarbose was used for diabetes prevention and cardiovascular endpoints were also evaluated. The incidence of type 2 diabetes can be significantly reduced by a "life-style-intervention" and also by the administration of metformin or acarbose. With acarbose cardiovascular events are reduced significantly and comparably to a therapy with statins in primary prevention.

引用

页码：S15 / +

页数：7

共 23 条

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[2]

[Anonymous], 1999, Diabetologia, V42, P647

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