High Frequency Deep Brain Stimulation of Superior Cerebellar Peduncles in a Patient with Cerebral Palsy

被引:16
作者
Lin, Suzhen [1 ,2 ]
Zhang, Chencheng [3 ]
Li, Hongxia [1 ,2 ]
Wang, Yuhan [3 ]
Wu, Yunhao [3 ]
Wang, Tao [3 ]
Pan, Yixin [3 ]
Sun, Bomin [3 ]
Wu, Yiwen [1 ,2 ]
Li, Dianyou [3 ]
机构
[1] Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Neurol, Sch Med, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Ruijin Hosp, Inst Neurol, Sch Med, Shanghai, Peoples R China
[3] Shanghai Jiao Tong Univ, Ruijin Hosp, Ctr Funct Neurosurg, Dept Neurosurg,Sch Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
Superior cerebellar peduncles; deep brain stimulation; dystonia; cerebral palsy; cerebellum; ANTERIOR LOBE; DYSTONIA;
D O I
10.5334/tohm.551
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Globus pallidus internus (GPi) deep brain stimulation (DBS) is widely used in patients with isolated dystonia; however, its use remains controversial in patients with acquired dystonia and cerebral palsy. Case presentation: We report the first case of a cerebral palsy patient, who failed to recover 2 years after GPi DBS; DBS was administered on both superior cerebellar peduncles (SCPs) and dentate nuclei (DNs). The monopolar stimulation results suggested that DBS was better administered via the SCPs than via the DNs. At six months follow-up, the patient exhibited a significant improvement of dystonia and spasticity, as well as in her quality of life. Discussion: SCP DBS may be a potential treatment for cerebral palsy patients with dystonia and spasticity who do not respond well to GPi DBS.
引用
收藏
页码:1 / 11
页数:11
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