Dramatic response of a gastrointestinal stromal tumor to neadjuvant imatinib therapy

被引:8
作者
Annaberdyev, Shohrat [1 ]
Gibbons, Joseph [2 ]
Hardacre, Jeffrey M. [1 ,3 ]
机构
[1] Case Western Reserve Univ, Sch Med, Cleveland, OH 44106 USA
[2] Univ Hosp Case Med Ctr, Div Hematol Oncol, Cleveland, OH USA
[3] Univ Hosp Case Med Ctr, Div Surg Oncol, Cleveland, OH USA
关键词
SURGICAL RESECTION; MESYLATE;
D O I
10.1186/1477-7819-7-30
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Gastrointestinal stromal tumors (GISTs) are the most common sarcoma of the alimentary tract and are believed to derive from the interstitial Cell of Cajal. Imatinib mesylate (Gleevec(R); Novartis, Basel, Switzerland) has revolutionized the treatment of GISTs and is generally used in the metastatic and adjuvant settings. We report the case of a 61-year old man who was treated with neoadjuvant imatinib for a massive gastric GIST with the hope of avoiding a potential multi-visceral resection.
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页数:3
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