Effects of ozone in equine jejunum reperfusion injury

被引：8

作者：

Alves, GES

Abreu, JMG

Ribeiro, JD

Muzzi, LAL

Oliveira, HP

Tannus, RJ

Buchanan, T

机构：

[1] Univ Fed Minas Gerais, Escola Vet, BR-30123970 Belo Horizonte, MG, Brazil

[2] Univ Estadual Ceara, Fortaleza, Ceara, Brazil

[3] Univ Fed Vicosa, Vicosa, MG, Brazil

[4] Univ Fed Lavras, Lavras, MG, Brazil

[5] Fac Jaguariuna, Jaguariuna, SP, Brazil

来源：

ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA | 2004年 / 56卷 / 04期

关键词：

equine; ozone; reperfusion; jejunum;

D O I：

10.1590/S0102-09352004000400002

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

This study was designed to investigate the effects of ozone on attenuating jejunum reperfusion injury in horses. Vascular obstruction(2h)reperfusion(12h) was induced and the animals received the following protocols: not treated (n=7, 500ml saline solution) or treated with ozone (n=6, 50mug.kg(-1)). Intestinal samples were histomorphologically examined at 0, 1, 2h (obstructive) and 1, 2, 12h (reperfusion phase). The following scores were significantly attenuated: mucosal region- epithelial loss, neutrophil infiltration and hemorrhage; submucosal region- neutrophil infiltration and edema. These effects may be related to the antioxidant enzyme modulation, or ozone biochemical properties, which interfered with biochemical steps of reperfusion injury. The results indicate an alternative for the treatment of equine acute abdomen.

引用

页码：433 / 437

页数：5