Current and Emerging Medical Therapies for Primary Hyperhidrosis

被引:45
作者
Grabell, Daniel A. [1 ]
Hebert, Adelaide A. [1 ,2 ]
机构
[1] UTHealth McGovern Med Sch, Dept Dermatol, Houston, TX 77030 USA
[2] UTHealth McGovern Med Sch, Dept Pediat, Houston, TX USA
关键词
Aluminum chloride; Botulinum toxin; Emerging therapies; Hyperhidrosis; Iontophoresis; TOXIN TYPE-A; PRIMARY PALMAR HYPERHIDROSIS; TAP-WATER IONTOPHORESIS; PRIMARY AXILLARY HYPERHIDROSIS; ALUMINUM-CHLORIDE HEXAHYDRATE; PLACEBO-CONTROLLED TRIAL; PRIMARY FOCAL HYPERHIDROSIS; QUALITY-OF-LIFE; SIDE-BY-SIDE; DOUBLE-BLIND;
D O I
10.1007/s13555-016-0148-z
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hyperhidrosis is defined as the production of sweat beyond what is physiologically necessary to maintain thermal homeostasis. This disease state may (and typically does) have a significant impact on the patient's quality of life. Medications including antiperspirants, anticholinergics, and botulinum toxin have been shown to be effective in the management of hyperhidrosis. Several medical device technologies have also proven to be effective. This review article will explore the current and emerging pharmacological and medical device treatments for hyperhidrosis and provide a framework for treating patients who suffer with primary forms of hyperhidrosis.
引用
收藏
页码:25 / 36
页数:12
相关论文
共 96 条
[1]   TREATMENT OF IDIOPATHIC HYPERHIDROSIS BY GLYCOPYRRONIUM BROMIDE AND TAP WATER IONTOPHORESIS [J].
ABELL, E ;
MORGAN, K .
BRITISH JOURNAL OF DERMATOLOGY, 1974, 91 (01) :87-91
[2]   Treatment of Primary Axillary Hyperhidrosis by Fractional Microneedle Radiofrequency: Is it Still Effective after Long-term Follow-up? [J].
Abtahi-Naeini, Bahareh ;
Naeini, Farahnaz Fatemi ;
Saffaei, Ali ;
Behfar, Shadi ;
Pourazizi, Mohsen ;
Mirmohammadkhani, Majid ;
Bolandnazar, Najmeh-Sadat .
INDIAN JOURNAL OF DERMATOLOGY, 2016, 61 (02) :234
[3]   PALMAR HYPERHIDROSIS AND ITS SURGICAL TREATMENT - REPORT OF 100 CASES [J].
ADAR, R ;
KURCHIN, A ;
ZWEIG, A ;
MOZES, M .
ANNALS OF SURGERY, 1977, 186 (01) :34-41
[4]  
Amir M, 2000, ISRAEL J PSYCHIAT, V37, P25
[5]  
Anliker MD, 2002, CURR PROBL DERMATOL, V30, P48
[6]   Botulinum toxin type A and other botulinum toxin serotypes: a comparative review of biochemical and pharmacological actions [J].
Aoki, KR ;
Guyer, B .
EUROPEAN JOURNAL OF NEUROLOGY, 2001, 8 :21-29
[7]   Pharmacokinetics, metabolism, and saliva output during transidermal and extended-release oral oxybutynin administration in healthy subjects [J].
Appell, RA ;
Chancellor, MB ;
Zobrist, RH ;
Thomas, H ;
Sanders, SW .
MAYO CLINIC PROCEEDINGS, 2003, 78 (06) :696-702
[8]  
Askari S, 2008, J AM ACAD DERMATOL, V58, pAB32
[9]   Prevalence and Disease Burden of Hyperhidrosis in the Adult Population [J].
Augustin, M. ;
Radtke, M. A. ;
Herberger, K. ;
Kornek, T. ;
Heigel, H. ;
Schaefer, I. .
DERMATOLOGY, 2013, 227 (01) :10-13
[10]   Use of oral glycopyrronium bromide in hyperhidrosis [J].
Bajaj, V. ;
Langtry, J. A. A. .
BRITISH JOURNAL OF DERMATOLOGY, 2007, 157 (01) :118-121