One-pot synthesis of 1-amidoalkyl-2-naphthols catalyzed by melamine-Br3 under solvent-free conditions

被引：17

作者：

Ghorbani-Choghamarani, Arash ^{[1
]}

Rashidimoghadam, Shima ^{[1
]}

机构：

[1] Ilam Univ, Fac Sci, Dept Chem, Ilam, Iran

来源：

CHINESE JOURNAL OF CATALYSIS | 2014年 / 35卷 / 07期

关键词：

Multi-component reaction; Amidoalkyl naphthol; Tribromo-melamine; Solvent-free; One-pot; DRUG-LIKE MOLECULES; AMIDOALKYL NAPHTHOLS; 1,1,1,3,3,3-HEXAMETHYLDISILAZANE HMDS; MULTICOMPONENT REACTION; HYDROXYL GROUP; SULFAMIC ACID; EFFICIENT; TRIMETHYLSILYLATION; TRIBROMOMELAMINE; MILD;

D O I：

10.1016/S1872-2067(14)60029-2

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A facile and efficient method has been developed for the synthesis of 1-amidoalkyl-2-naphthols via the one-pot multi-component condensation of 2-naphthol with aromatic aldehydes and acetamide or thioacetamide in the presence of melamine-Br-3 under solvent-free conditions. There are several advantages to this reaction, including high yields, short reaction time, and high catalytic efficiency. (C) 2014, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：1024 / 1029

页数：6

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