N-[2-(azepan-1-yl)-9-isopropyl-9H-purin-6-yl]-4-methoxybenzylamine

被引：8

作者：

Trávnícek, Z

Zatloukal, M

机构：

[1] Palacky Univ, Fac Sci, Dept Inorgan Chem, CZ-77147 Olomouc, Czech Republic

[2] Palacky Univ, Lab Growth Regulators, CZ-78371 Olomouc, Czech Republic

[3] Palacky Univ, AS CR, Inst Expt Bot, CZ-78371 Olomouc, Czech Republic

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2004年 / 60卷

关键词：

D O I：

10.1107/S1600536804010207

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C22H30N6O, is a potent inhibitor of estrogen sulfotransferase which catalyses the transfer of a sulfuryl group from 3'-phosphoadenosine 5'-phosphosulfate to estrogen and estrogen-like compounds. The pyrimidine plane forms dihedral angles of 81.53 (4) and 2.99 (4)degrees with the benzene and imidazole rings, respectively. The crystal structure is stabilized by N-H...N hydrogen bonds connecting two adjacent molecules, thus forming centrosymmetric dimers, the N...N distance being 3.0403 (16) Angstrom.

引用

页码：O924 / O926

页数：3

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