The use of liposomes in the modification of polycaprolactone fibers

被引:4
作者
Batory, Mirella [1 ]
Adamus-Grabicka, Angelika [2 ]
Sobczyk-Guzenda, Anna [3 ]
Bartoszek, Nina [4 ]
Komorowski, Piotr [4 ,5 ]
Vyslouzilova, Lucie [6 ]
Rozek, Zbigniew [6 ]
Budzisz, Elzbieta [2 ]
机构
[1] Med Univ Lodz, Fac Pharm, Dept Cosmetol & Aesthet Dermatol, Lodz, Poland
[2] Med Univ Lodz, Fac Pharm, Dept Cosmet Raw Mat Chem, Lodz, Poland
[3] Lodz Univ Technol, Inst Mat Sci & Engn, Dept Engn Coatings & Nonmetall Mat, Lodz, Poland
[4] Lodz Reg Pk Sci & Technol, BioNanoPark Labs, Mol & Nanostruct Biophys Unit, Lodz, Poland
[5] Lodz Univ Technol, Inst Mat Sci & Engn, Dept Biophys, Lodz, Poland
[6] Tech Univ Liberec, Fac Text Engn, Dept Nonwovens & Nanofibrous Mat, Liberec, Czech Republic
关键词
electrospinning; fibers; functionalization of polymers; properties and characterization; DRUG-LOADED NANOFIBERS; DELIVERY-SYSTEMS; TOPICAL DELIVERY; IN-VITRO; MATS; NANOPARTICLES; ACYCLOVIR; VITAMIN; ACID;
D O I
10.1002/app.43299
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Polycaprolactone is fully bioresorbable and biocompatible material. Liposomes containing nanocopper, nanosilver, and nanogold are known to have antifungal and antibacterial properties and to further aid in the synthesis of collagen and elastin in the skin. It is possible to combine the properties of polycaprolactone fibers and liposomes in new approaches to deliver active substances through cosmetics and medicines. The aim of the research was to examine the possibility of simple modification of PCL fibers with use of nanocopper, nanogold, and nanosilver incorporated liposomes. The size and the type of the liposomes were examined using optical microscopy and DLS techniques. The fibres modified with liposomes were investigated using SEM and FTIR techniques. Additionally the contact angle measurements were performed. The study shows an innovative method of modifying polycaprolactone nonwoven textiles. This combination of PCL fibers and liposomes allows easy and efficient preparation and delivery of active substances to a particular location. (c) 2015 Wiley Periodicals, Inc.
引用
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页数:7
相关论文
共 50 条
[1]  
[Anonymous], 1991, Spectrometric identification of organic compounds
[2]  
Arsic I., 1999, International Journal of Cosmetic Science, V21, P219, DOI 10.1046/j.1467-2494.1999.181682.x
[3]  
Azarbayjani AF, 2010, J PHARM PHARM SCI, V13, P400
[4]   Eco-designed biohybrids based on liposomes, mint-nanosilver and carbon nanotubes for antioxidant and antimicrobial coating [J].
Barbinta-Patrascu, M. E. ;
Ungureanu, Camelia ;
Iordache, Stefan Marian ;
Iordache, Ana Maria ;
Bunghez, Ioana-Raluca ;
Ghiurea, Marius ;
Badea, Nicoleta ;
Fierascu, Radu-Claudiu ;
Stamatin, Ioan .
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2014, 39 :177-185
[5]  
Bartosiewicz D., 2008, DRUG POLAND, V18, P85
[6]   Silver implanted diamond-like carbon coatings [J].
Batory, D. ;
Gorzedowski, J. ;
Rajchel, B. ;
Szymanski, W. ;
Kolodziejczyk, L. .
VACUUM, 2014, 110 :78-86
[7]  
Benson Heather A. E., 2005, Current Drug Delivery, V2, P23, DOI 10.2174/1567201052772915
[8]   Biological properties of "naked" metal nanoparticles [J].
Bhattacharya, Resham ;
Mukherjee, Priyabrata .
ADVANCED DRUG DELIVERY REVIEWS, 2008, 60 (11) :1289-1306
[9]   Dermal and transdermal drug delivery systems: Current and future prospects [J].
Brown, MB ;
Martin, GP ;
Jones, SA ;
Akomeah, FK .
DRUG DELIVERY, 2006, 13 (03) :175-187
[10]   Electrohydrodynamics: A facile technique to fabricate drug delivery systems [J].
Chakraborty, Syandan ;
Liao, I-Chien ;
Adler, Andrew ;
Leong, Kam W. .
ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (12) :1043-1054