Pathogenesis of Helicobacter pylori Infection

被引：30
作者：
de Bernard, Marina [1 ]
Josenhans, Christine [2 ]
机构：
[1] Univ Padua, Dept Biol, I-35121 Padua, Italy
[2] Hannover Med Sch, Inst Med Microbiol & Hosp Epidemiol, D-30625 Hannover, Germany
来源：
HELICOBACTER | 2014年 / 19卷
关键词：
VacA; CagA; Type IV secretion system; gamma-glutamyl-transpeptidase; cancerogenesis; GAMMA-GLUTAMYL-TRANSPEPTIDASE; GASTRIC EPITHELIAL-CELLS; IV SECRETION SYSTEM; STRUCTURAL INSIGHTS; CAGA ONCOPROTEIN; COLONIZATION; ACTIVATION; EXPRESSION; COMPLEX; MECHANISM;
D O I：
10.1111/hel.12160
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Helicobacter pylori relies on multiple colonization and virulence factors to persist in the human stomach for life. In addition, these factors can be modulated and vary to suit the ever-changing environment within the host individual. This article outlines the novel developments in this field of research during the past year, highlighting the cag pathogenicity island, VacA, gamma-glutamyl-transpeptidase as well as including recent advances in protein structure, bacteria host interaction, and the role of stomach microbiota.
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收藏
页码：11 / 18
页数：8
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