Recent Applications of Click Reaction in the Syntheses of 1,2,3-triazoles

被引：50

作者：

Heravi, Majid M. ^{[1
]}

Hamidi, Hoda ^{[1
]}

Zadsirjan, Vahideh ^{[1
]}

机构：

[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran

来源：

CURRENT ORGANIC SYNTHESIS | 2014年 / 11卷 / 05期

关键词：

1,2,3-triazoles; azides; bis-1,2,3-triazoles; click reaction; cycloaddition; heterocycles; fused 1,2,3-triazoles; ONE-POT SYNTHESIS; COPPER IODIDE NANOPARTICLES; CYCLOADDITION EN-ROUTE; ACTION HIV-1 PROTEASE; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; COUMARIN DERIVATIVES; EFFICIENT SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; PHOTOPHYSICAL PROPERTIES; ANTITUBERCULAR ACTIVITY;

D O I：

10.2174/1570179411666140530210314

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Triazoles and their derivatives have been widely utilized as precursors in the syntheses of biologically active systems such as anticancers, antimicrobials, antifungals and other cytotoxic active agents. In this review, we tried to highlight the recent advances (2010-2013) in the syntheses of 1,2,3-triazoles, bis-1,2,3-triazoles and fused triazoles via click reaction. Click reaction provides substances quickly and reliably by combining small units together. Click chemistry can also be applied widely for the syntheses of biologically active compounds. Since the 1,2,3-triazole scaffold is present in many beneficial biologically structures, we hope this review attracts the attentions of synthetic organic chemists to make use of the advantages of click reaction in the total syntheses of natural products containing 1,2,3-triazoles.

引用

页码：647 / 675

页数：29

共 50 条

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