2-Methyl-3,5,6-triphenyl-2,3-dihydropyrazine

被引：2

作者：

Anuradha, N. ^{[1
]}

Thiruvalluvar, A. ^{[1
]}

Pandiarajan, K. ^{[2
]}

Chitra, S. ^{[2
]}

Butcher, R. J. ^{[3
]}

机构：

[1] Rajah Serfoji Govt Coll Autonomous, Postgrad Res Dept Phys, Thanjavur 613005, Tamil Nadu, India

[2] Annamalai Univ, Dept Chem, Annamalainagar 608002, Tamil Nadu, India

[3] Howard Univ, Dept Chem, Washington, DC 20059 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷

关键词：

D O I：

10.1107/S1600536809005042

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title molecule, C23H20N2, the heterocyclic ring adopts a screw-boat conformation, with all substituents equatorial. The phenyl ring at position 3 makes dihedral angles of 78.12 (15) and 72.67 (15)degrees, respectively, with the phenyl rings at positions 5 and 6; the dihedral angle between the phenyl rings at positions 5 and 6 is 67.32 (14)degrees. A C-H center dot center dot center dot pi interaction is present in the crystal structure.

引用

页码：O546 / U2032

页数：10

共 9 条

[1] BALIAH V, 1978, INDIAN J CHEM B, V16, P73
[2] SIR2004:: an improved tool for crystal structure determination and refinement
Burla, MC
Caliandro, R
Camalli, M
Carrozzini, B
Cascarano, GL
De Caro, L
Giacovazzo, C
Polidori, G
Spagna, R
[J]. JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2005, 38 : 381 - 388
[3] Farrujia LJ., 1997, J APPL CRYSTALLOGR, V30, P565, DOI [10.1107/S0021889897003117, DOI 10.1107/S0021889897003117]
[4] Oxford Diffraction, 2008, CrysAlis CCD and CrysAlis RED Versions 1.171.32.24
[5] A short history of SHELX
Sheldrick, George M.
[J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 : 112 - 122
[6] Synthesis and biological evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors
Singh, SK
Saibaba, V
Ravikumar, V
Rudrawar, SV
Daga, P
Rao, CS
Akhila, V
Hegde, P
Rao, YK
[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (08) : 1881 - 1893
[7] Structure validation in chemical crystallography
Spek, Anthony L.
[J]. ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2009, 65 : 148 - 155
[8] Growth inhibition and mutagenesis induced in Escherichia coli by dihydropyrazines with DNA strand-cleaving activity
Takechia, S
Yamaguchi, T
Nomura, H
Minematsu, T
Nakayama, T
[J]. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2004, 560 (01) : 49 - 55
[9] The behavior of dihydropyrazine with DNA strand-breakage activity in vivo
Yamaguchi, T
Nomura, H
Matsunaga, K
Ito, S
Takata, J
Karube, Y
[J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2003, 26 (11) : 1523 - 1527

← 1 →