Optimal Interval Type-2 Fuzzy Logic Control Based Closed-Loop Regulation of Mean Arterial Blood Pressure Using the Controlled Drug Administration

In pandemic times, the remote and automatic control/observation of physiological variables of the patients is the prime necessity for healthcare technologies. The closed-loop regulation of mean arterial pressure is essential for critically ill patients or post-surgery recovery patients. The physiological variables have serious issues such as parameter variations and uncertainties. In this paper, an interval type-2 fuzzy logic controller (IT2FLC) with footprints of uncertainty in the membership functions is presented in a two-layered design (TL-IT2FLC) that can efficiently deal with uncertainties and parameter variations. In this design, a pre-compensator IT2FLC is used, which deals with the uncertainties and parameter variations before the primary IT2FLC approach. The robustness analysis of the proposed method is investigated for external noise, and results are compared with traditional PID and T1-FLC techniques.