Application of basic clays in microwave activated Michael additions: Preparation of N-substituted imidazoles

被引：27

作者：

MartinAranda, RM ^{[1
]}

VicenteRodriguez, MA ^{[1
]}

LopezPestana, JM ^{[1
]}

LopezPeinado, AJ ^{[1
]}

Jerez, A ^{[1
]}

LopezGonzalez, JDD ^{[1
]}

BanaresMunoz, MA ^{[1
]}

机构：

[1] UNIV SALAMANCA,DEPT QUIM INORGAN,E-37008 SALAMANCA,SPAIN

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1997年 / 124卷 / 2-3期

关键词：

Michael addition; alkaline montmorillonites; microwave irradiation; imidazole;

D O I：

10.1016/S1381-1169(97)00070-8

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Imidazole (C3H4N2) was condensed with ethyl acrylate (C5H8O2) using two basic clays (Li+ and Cs+ montmorillonites) as catalysts in a microwave oven. The catalysts were characterized by chemical analyses, nitrogen adsorption isotherms and X-ray diffraction. Under these experimental conditions N-substituted heterocycles can be obtained with a high activity and selectivity. The role of alkali promoters (Li+ and Cs+) in the montmorillonite for the Michael addition was studied. It was evidenced that the greater the basicity and the irradiation time and power of irradiation were, the higher were the conversion. The yield of the N-substituted imidazole presents a maximum for 0.1 g of Cs-montmorillonite at 850 W in only 5 min of irradiation. (C) 1997 Elsevier Science B.V.

引用

页码：115 / 121

页数：7

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