Biological actions of Cu/Zn coimplanted TiN on Ti-6Al-4V alloy

被引：12

作者：

Li, Qingling ^{[1
,2
]}

Li, Li ^{[1
,2
]}

Zhao, Mengli ^{[1
,2
]}

Dong, Lei ^{[1
,2
]}

Wu, Jie ^{[1
,2
]}

Li, Dejun ^{[1
,2
]}

机构：

[1] Tianjin Normal Univ, Coll Phys & Mat Sci, Tianjin 300387, Peoples R China

[2] Tianjin Normal Univ, Tianjin Int Joint Res Ctr Surface Technol Energy, Tianjin 300387, Peoples R China

来源：

BIOINTERPHASES | 2019年 / 14卷 / 05期

基金：

中国国家自然科学基金;

关键词：

ION-IMPLANTATION; ANTIBACTERIAL PROPERTIES; CORROSION-RESISTANCE; OSTEOGENIC ACTIVITY; THIN-FILMS; TITANIUM; COATINGS; BEHAVIOR; BIOCOMPATIBILITY; CU;

D O I：

10.1116/1.5116640

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Ti-6Al-4V alloy, as a widely used orthopedic and dental implant, has excellent biocompatibility and machinability. However, its poor corrosion resistance and antibacterial property may lead to tissue inflammation and postoperative infection, which hinders its further development. In this paper, to solve the above problems, copper (Cu) and zinc (Zn) ions were coimplanted into a titanium nitride (TiN) coated Ti-6Al-4V alloy via a plasma immersion ion implantation system (PIII). Then, the structure and composition of Cu/Zn coimplanted TiN (Cu/Zn-TiN-PIII) were characterized by scanning electron microscopy and x-ray photoelectron spectroscopy. Also, the results of the corrosion test, the water contact angles test, and the protein electrophoresis experiment showed that the corrosion resistance, hydrophilicity, and the protein adsorption capacity of Cu/Zn-TiN-PIII were improved simultaneously. In addition, compared with TiN-PIII, Cu/Zn-TiN-PIII promoted both cytocompatibility and the antibacterial property according to L929 cells and Escherichia coli assays in vitro. Therefore, Cu/Zn-TiN-PIII may be a good candidate for orthopedic implants.

引用

页数：7

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