Positive views on antipsychotic long-acting injections: results of a survey of community patients prescribed antipsychotics

被引:12
作者
Mace, Shubhra [1 ,2 ]
Chak, Oscar [1 ]
Punny, Sharanjeet [1 ]
Sedough-Abbasian, Daniel [1 ]
Vegad, Chirag [3 ]
Taylor, David M. [1 ,4 ]
机构
[1] Maudsley Hosp & Inst Psychiat, Pharm Dept, Denmark Hill, London SE5 8AZ, England
[2] Kings Coll London, Inst Pharmaceut Sci, 5th Floor,Franklin Wilkins Bldg,150 Stamford St, London SE1 9NH, England
[3] Kings Coll Hosp London, Pharm Dept, Denmark Hill, London, England
[4] Kings Coll London, Inst Pharmaceut Sci, London, England
关键词
antipsychotic; depot; long-acting injection; patient survey; INJECTABLE ANTIPSYCHOTICS; ATTITUDES; DEPOT; PSYCHIATRISTS; MEDICATION; SCHIZOPHRENIA; NONADHERENCE; MANAGEMENT;
D O I
10.1177/2045125319860977
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background: We aimed to assess patients' views about antipsychotic long-acting injections (LAIs). Methods: We interviewed patients prescribed an antipsychotic (oral or LAI) in our community teams. In a subanalysis, responses were analysed for differences between patients currently receiving an LAI and those prescribed only oral medication. Results: In total, 226 patients (57%) completed the study questionnaire. The majority agreed that LAIs ensured delivery of the right amount of medication and protection against hospital admissions (57% and 60%, respectively). A minority of participants were more concerned than not about the use of a needle (46%), pain from injection (48%) and the need to travel to receive the injection (34%). A majority expressed a preference for injection site (deltoid or gluteal) (65%) and clinic location (69%). A higher proportion of patients currently receiving an LAI compared with those prescribed oral medication thought an LAI was beneficial because this formulation obviated the need to: swallow tablets (63% versus 41%; p = 0.0013), remember to take tablets daily (75% versus 51%; p = 0.0004), remember tablets when away from home (72% versus 49%; p = 0008). Current LAI users were more likely than those on oral treatment to agree that LAIs keep patients out of hospital (76% versus 44%; p = 0.0001) and that the injection ensured delivery of the right amount of medication (71% versus 44%; p = 0.0002). Women were more likely than men to prefer administration by a clinician of the same gender (34% versus 12%; p = 0.0001). Conclusions: In our study, a greater proportion of patients prescribed an LAI regarded LAIs as beneficial compared with those on oral medication.
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页数:7
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