Concomitant Genetic Alterations With Response to Treatment and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With EGFR-Mutant Advanced Non-Small Cell Lung Cancer

被引:148
作者
Hong, Shaodong [1 ,2 ,3 ]
Gao, Fangfang [1 ,2 ,3 ]
Fu, Sha [4 ]
Wang, Yan [5 ]
Fang, Wenfeng [1 ,2 ,3 ]
Huang, Yan [1 ,2 ,3 ]
Zhang, Li [1 ,2 ,3 ]
机构
[1] State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China
[2] Collaborat Innovat Ctr Canc Med, Guangzhou, Guangdong, Peoples R China
[3] Sun Yat Sen Univ, Dept Med Oncol, Ctr Canc, 651 Dongfeng East Rd, Guangzhou 510060, Guangdong, Peoples R China
[4] Sun Yat Sen Univ, Guangdong Prov Key Lab Malignant Tumor Epigenet &, Dept Pathol, Sun Yat Sen Mem Hosp, Guangzhou, Peoples R China
[5] Quest Genom, Nanjing, Jiangsu, Peoples R China
基金
国家重点研发计划;
关键词
CHEMOTHERAPY; METAANALYSIS; IMPACT;
D O I
10.1001/jamaoncol.2018.0049
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:739 / 742
页数:5
相关论文
共 6 条
  • [1] Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers
    Blakely, Collin M.
    Watkins, Thomas B. K.
    Wu, Wei
    Gini, Beatrice
    Chabon, Jacob J.
    McCoach, Caroline E.
    McGranahan, Nicholas
    Wilson, Gareth A.
    Birkbak, Nicolai J.
    Olivas, Victor R.
    Rotow, Julia
    Maynard, Ashley
    Wang, Victoria
    Gubens, Matthew A.
    Banks, Kimberly C.
    Lanman, Richard B.
    Caulin, Aleah F.
    St John, John
    Cordero, Anibal R.
    Giannikopoulos, Petros
    Simmons, Andrew D.
    Mack, Philip C.
    Gandara, David R.
    Husain, Hatim
    Doebele, Robert C.
    Riess, Jonathan W.
    Diehn, Maximilian
    Swanton, Charles
    Bivona, Trever G.
    [J]. NATURE GENETICS, 2017, 49 (12) : 1693 - +
  • [2] Impact of Specific Epidermal Growth Factor Receptor (EGFR) Mutations and Clinical Characteristics on Outcomes After Treatment With EGFR Tyrosine Kinase Inhibitors Versus Chemotherapy in EGFR-Mutant Lung Cancer: A Meta-Analysis
    Lee, Chee Khoon
    Wu, Yi-Long
    Ding, Pei Ni
    Lord, Sarah J.
    Inoue, Akira
    Zhou, Caicun
    Mitsudomi, Tetsuya
    Rosell, Rafael
    Pavlakis, Nick
    Links, Matthew
    Gebski, Val
    Gralla, Richard J.
    Yang, James Chih-Hsin
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (17) : 1958 - U142
  • [3] Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors vs Conventional Chemotherapy in Non-Small Cell Lung Cancer Harboring Wild-Type Epidermal Growth Factor Receptor A Meta-analysis
    Lee, June-Koo
    Hahn, Seokyung
    Kim, Dong-Wan
    Suh, Koung Jin
    Keam, Bhumsuk
    Kim, Tae Min
    Lee, Se-Hoon
    Heo, Dae Seog
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 311 (14): : 1430 - 1437
  • [4] Gefitinib or Chemotherapy for Non-Small-Cell Lung Cancer with Mutated EGFR.
    Maemondo, Makoto
    Inoue, Akira
    Kobayashi, Kunihiko
    Sugawara, Shunichi
    Oizumi, Satoshi
    Isobe, Hiroshi
    Gemma, Akihiko
    Harada, Masao
    Yoshizawa, Hirohisa
    Kinoshita, Ichiro
    Fujita, Yuka
    Okinaga, Shoji
    Hirano, Haruto
    Yoshimori, Kozo
    Harada, Toshiyuki
    Ogura, Takashi
    Ando, Masahiro
    Miyazawa, Hitoshi
    Tanaka, Tomoaki
    Saijo, Yasuo
    Hagiwara, Koichi
    Morita, Satoshi
    Nukiwa, Toshihiro
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (25) : 2380 - 2388
  • [5] Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer
    Soria, J. -C.
    Ohe, Y.
    Vansteenkiste, J.
    Reungwetwattana, T.
    Chewaskulyong, B.
    Lee, K. H.
    Dechaphunkul, A.
    Imamura, F.
    Nogami, N.
    Kurata, T.
    Okamoto, I.
    Zhou, C.
    Cho, B. C.
    Cheng, Y.
    Cho, E. K.
    Voon, P. J.
    Planchard, D.
    Su, W. -C.
    Gray, J. E.
    Lee, S. -M.
    Hodge, R.
    Marotti, M.
    Rukazenkov, Y.
    Ramalingam, S. S.
    Boyer, Michael
    Lee, Chee
    Hughes, Brett
    O'Byrne, Kenneth
    Briggs, Peter
    Milward, Michael
    John, Thomas
    Demedts, Ingel
    Vansteenkiste, Johan
    Bustin, Frederique
    Barrios, Carlos Henrique
    Timcheva, Constanta
    Butts, Charles
    Goss, Glenwood
    Juergens, Rosalyn
    Leighl, Natasha
    Cheng, Susanna
    Burkes, Ronald
    Zhou, Caicun
    Zhang, Helong
    Shu, Yongqian
    Cheng, Ying
    Zhou, Qing
    Li, Wei
    Feng, Guosheng
    He, Yong
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (02) : 113 - 125
  • [6] Circulating tumor DNA identified by targeted sequencing in advanced-stage non-small cell lung cancer patients
    Xu, Song
    Lou, Feng
    Wu, Yi
    Sun, Da-Qiang
    Zhang, Jing-Bo
    Chen, Wei
    Ye, Hua
    Liu, Jing-Hao
    Wei, Sen
    Zhao, Ming-Yu
    Wu, Wen-Jun
    Su, Xue-Xia
    Shi, Rong
    Jones, Lindsey
    Huang, Xue F.
    Chen, Si-Yi
    Chen, Jun
    [J]. CANCER LETTERS, 2016, 370 (02) : 324 - 331