No evidence for impaired 'theory of mind' in unaffected first-degree relatives of schizophrenia patients

被引:73
作者
Kelemen, O
Kéri, S
Must, A
Benedek, G
Janka, Z
机构
[1] Univ Szeged, Dept Psychiat, H-672S Szeged, Hungary
[2] Bacs Kiskun Cty Hosp, Ctr Psychiat, Kecskemet, Hungary
[3] Univ Szeged, Dept Physiol, H-672S Szeged, Hungary
关键词
schizophrenia; theory of mind; Eyes Test; endophenotype; genetic liability; cognitive dysfunction;
D O I
10.1111/j.1600-0047.2004.00357.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: The aim of this study was to investigate the possibility that 'theory of mind' (ToM) impairments are associated with schizophrenia liability. Method: Forty healthy control subjects and 79 first-degree biological relatives of schizophrenia patients (32 siblings and 47 parents) received the Eyes Test, during which subjects are asked to choose the word best describes the mental state of a person whose eyes are depicted on a photograph. Results: The affected relatives (n = 14) performed worse on the Eyes Test compared with the controls (P = 0.0001), whereas the unaffected relatives (n = 65) showed intact performances (P = 0.4). The Eyes Test values did not correlate with age and IQ. There was no significant difference between male and female participants. Conclusion: ToM deficits, as measured by the Eyes Test, are not associated with schizophrenia liability.
引用
收藏
页码:146 / 149
页数:4
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