A stromal PTEN/STAT3 signaling axis promotes immune evasion and tumor progression in pancreatic cancer.

被引:0
|
作者
MarElia-Bennett, Catherine B. [1 ]
Lefler, Julia E. [1 ]
Ostrowski, Michael C. [1 ]
机构
[1] Med Univ South Carolina, Charleston, SC 29425 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PO-054
引用
收藏
页数:2
相关论文
共 50 条
  • [21] STAT3 signaling in the tumor microenvironment promotes primary gastric cancer growth and metastasis formation
    Eissmann, Moritz
    Huber, Anne
    Allam, Amr
    Dijkstra, Christine
    Ernst, Matthias
    CANCER RESEARCH, 2022, 82 (12)
  • [22] YAP1 induces bladder cancer progression and promotes immune evasion through IL-6/STAT3 pathway and CXCL deregulation
    Sadhukhan, Pritam
    Feng, Mingxiao
    Illingworth, Emily
    Sloma, Ido
    Ooki, Akira
    Matoso, Andres
    Sidransky, David
    Johnson III, Burles A.
    Marchionni, Luigi
    Sille, Fenna C. M.
    Choi, Woonyoung
    Mcconkey, David
    Hoque, Mohammad
    JOURNAL OF CLINICAL INVESTIGATION, 2025, 135 (02):
  • [23] ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis
    Chen, Changliang
    Gupta, Prachi
    Parashar, Deepak
    Nair, Gopakumar G.
    George, Jasmine
    Geethadevi, Anjali
    Wang, Wei
    Tsaih, Shirng-Wern
    Bradley, William
    Ramchandran, Ramani
    Rader, Janet S.
    Chaluvally-Raghavan, Pradeep
    Pradeep, Sunila
    ONCOGENE, 2020, 39 (14) : 2921 - 2933
  • [24] ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis
    Changliang Chen
    Prachi Gupta
    Deepak Parashar
    Gopakumar G. Nair
    Jasmine George
    Anjali Geethadevi
    Wei Wang
    Shirng-Wern Tsaih
    William Bradley
    Ramani Ramchandran
    Janet S. Rader
    Pradeep Chaluvally-Raghavan
    Sunila Pradeep
    Oncogene, 2020, 39 : 2921 - 2933
  • [25] DNMT3a promotes proliferation by activating the STAT3 signaling pathway and depressing apoptosis in pancreatic cancer
    Jing, Wei
    Song, Na
    Liu, Yun-Peng
    Qu, Xiu-Juan
    Qi, Ya-Fei
    Li, Ce
    Hou, Ke-Zuo
    Che, Xiao-Fang
    Yang, Xiang-Hong
    CANCER MANAGEMENT AND RESEARCH, 2019, 11 : 6379 - 6396
  • [26] STAT3 Mediates Regulation of the Tumor Microenvironment in Pancreatic Cancer
    Nagathihalli, N. S.
    Beesetty, Y.
    Reyzer, M.
    Shi, C.
    Caprioli, R.
    Merchant, N. B.
    PANCREAS, 2011, 40 (08) : 1342 - 1342
  • [27] Melanoma cell-intrinsic TNFAIP3 promotes tumor progression and immune escape by activating STAT3
    Ma, J.
    Guo, W.
    Wang, S.
    Guo, S.
    Gao, T.
    Li, C.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2018, 138 (05) : S204 - S204
  • [28] IL22RA1/STAT3 Signaling Promotes Stemness and Tumorigenicity in Pancreatic Cancer
    He, Weizhi
    Wu, Jinghua
    Shi, Juanjuan
    Huo, Yan-Miao
    Dai, Wentao
    Geng, Jing
    Lu, Ping
    Yang, Min-Wei
    Fang, Yuan
    Wang, Wei
    Zhang, Zhi-Gang
    Habtezion, Aida
    Sun, Yong-Wei
    Xue, Jing
    CANCER RESEARCH, 2018, 78 (12) : 3293 - 3305
  • [29] Transcription factor Stat3 promotes metastatic progression of prostate cancer
    Gu, Lei
    Abdulghani, Junaid
    Dagvadorj, Ayush
    Lutz, Jacqueline
    Bonuccelli, Gloria
    Lisanti, Michael P.
    Zellweger, Tobias
    Alanen, Kalle
    Mirtti, Tuomas
    Visakorpi, Tapio
    Bubendorf, Lukas
    Nevalainen, Marja T.
    JOURNAL OF UROLOGY, 2008, 179 (04): : 392 - 392
  • [30] Ubiquitin specific peptidase 5 enhances STAT3 signaling and promotes migration and invasion in Pancreatic Cancer
    Lian, Jie
    Liu, Chao
    Guan, Xin
    Wang, Bojun
    Yao, Yuanfei
    Su, Dan
    Ma, Yue
    Fang, Lin
    Zhang, Yanqiao
    JOURNAL OF CANCER, 2020, 11 (23): : 6802 - 6811