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Papillomavirus Infection in Humans and Dromedary Camels in Eastern Sudan
被引:1
作者:
Khalafalla, Abdelmalik I.
[1
,2
]
Rector, Annabel
[3
]
Elfadl, Ahmed K.
[4
]
机构:
[1] Univ Khartoum, Dept Microbiol, Fac Vet Med, POB 32, Khartoum 1334, Sudan
[2] Abu Dhabi Food Control Author, Abu Dhabi, U Arab Emirates
[3] Katholieke Univ Leuven, Dept Microbiol & Immunol, Lab Clin & Epidemiol Virol, Leuven, Belgium
[4] Univ Khartoum, Dept Pathol, Fac Vet Med, Khartoum, Sudan
关键词:
papillomavirus infection;
humans;
dromedary camels;
eastern Sudan;
PAPILLOMATOSIS;
GENOMES;
VIRUS;
D O I:
10.1089/vbz.2017.2242
中图分类号:
R1 [预防医学、卫生学];
学科分类号:
1004 ;
120402 ;
摘要:
Cases of wart-like lesions in humans and dromedary camels occurred in eastern Sudan in 2015 were described. Involvement of papillomavirus (PV) in causing these cases was affirmed by PCR and immunoperoxidase test. Mostly, the lesions were observed on the skin of the chest and forearms in addition to lips and mandible. Sequence analysis revealed Camelus dromedarius PV types 1 and 2 genotypes as the causative genotypes. We also observed cases of wart-like lesions on hands and legs of two herders attending the infected camel herd. Partial genome sequencing revealed human PV type 2 in one of the two human samples providing no indications for interspecies transmission of camel PVs, yet provides, for the first time evidence of active circulation of this virus in eastern Sudan.
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页码:440 / 444
页数:5
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