Ring transformation of fused pyridazines .6. Construction of 3-(2-pyridyl)indole skeleton by means of N-N bond cleavage reaction of fused pyridazines with ynamines

被引：7

作者：

Iwamoto, K ^{[1
]}

Oishi, E ^{[1
]}

Sano, T ^{[1
]}

Tsuchiya, A ^{[1
]}

Suzuki, Y ^{[1
]}

Higashino, T ^{[1
]}

Miyashita, A ^{[1
]}

机构：

[1] UNIV SHIZUOKA,GRAD SCH NUTR & ENVIRONM SCI,DIV ENVIRONM HLTH SCI,SHIZUOKA 422,JAPAN

来源：

HETEROCYCLES | 1997年 / 45卷 / 08期

关键词：

D O I：

10.3987/COM-97-7847

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We established a new N-N bond cleavage reaction of pyridazino[4,5-b]indoles with ynamines to form 3-(2-pyridyl)indoles. The latter are easily converted to 3-(2-piperidyl)indoles, which are key intermediates for the synthesis of indole alkaloids.

引用

页码：1551 / 1557

页数：7

共 3 条

[1] BRIDGEHEAD NITROGEN HETEROCYCLES .6. SYNTHESIS AND CHARACTERIZATION OF SOME RING-FUSED 3-SUBSTITUTED 3H-[1,2,4]THIADIAZOLOPYRIMIDINES,-PYRAZINES, AND PYRIDAZINES
POTTS, KT
KANE, J
JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (18): : 3087 - 3090
[2] FREE-RADICAL REACTIONS OF N-HETEROCYCLIC COMPOUNDS .6. RADICAL REACTIONS OF CYCLIC 2,2-DIACYL-1-ARYLHYDRAZYLS - A NEW N-N BOND-CLEAVAGE REACTION
SCHULZ, M
KLUGE, R
WILLSCHER, S
LIEBIGS ANNALEN DER CHEMIE, 1987, (08): : 671 - 678
[3] Cu(NO3)2•3H2O-mediated synthesis of 4′-(2-pyridyl)-2,2′:6′,2"-terpyridine (L2) from N-(2-pyridylmethyl) pyridine-2-methylketimine (L1).: A C-C bond-forming reaction and the structure of {[Cu(L2)( OH)(NO3)][Cu(L2)(NO3)2]}•2H2O
Padhi, Sumanta Kumar
Manivannan, Vadivelu
INORGANIC CHEMISTRY, 2006, 45 (20) : 7994 - 7996

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