Uterine Factors

被引：39
作者：
Jaslow, Carolyn R. [1 ]
机构：
[1] Rhodes Coll, Dept Biol, Memphis, TN 38112 USA
来源：
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2014年 / 41卷 / 01期
关键词：
Recurrent miscarriage; Uterus; Septum; Fibroids; Uterine anomalies; Pregnancy loss; Congenital; Acquired; RECURRENT SPONTANEOUS-ABORTION; FEMALE GENITAL-TRACT; VELOCITY WAVE-FORMS; ENDOMETRIAL POLYPS; MULLERIAN DUCT; INTRAUTERINE ADHESIONS; REPRODUCTIVE OUTCOMES; HYSTEROSCOPIC METROPLASTY; SEPTATE UTERUS; CYTOGENETIC ABNORMALITIES;
D O I：
10.1016/j.ogc.2013.10.002
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Uterine anomalies are one of the most common parental causes of recurrent pregnancy loss, occurring in about 19% of patients. Congenital uterine anomalies are most likely caused by HOX gene mutations, although the mechanism is probably polygenic. There are no known environmental causes other than estrogenic endocrine disruptors such as diethylstilbestrol. Acquired uterine anomalies may result from uterine trauma (adhesions) or benign growths of the myometrium (fibroids) or endometrium (polyps). Although randomized controlled trials are lacking, surgical treatment is recommended for repair of uterine septa, and for removal of severe adhesions and submucosal fibroids, especially if no other causes are identified.
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页码：57 / +
页数：32
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