Auricular Acupressure Reduces Anxiety Levels and Improves Outcomes of in Vitro Fertilization: A Prospective, Randomized and Controlled Study

被引：41

作者：

Qu, Fan ^{[1
,2
,3
]}

Zhang, Dan ^{[1
,2
,3
]}

Chen, Lu-Ting ^{[1
]}

Wang, Fang-Fang ^{[1
,2
,3
]}

Pan, Jie-Xue ^{[1
]}

Zhu, Yi-Min ^{[1
,2
,3
]}

Ma, Chun-Mei ^{[1
]}

Huang, Yi-Ting ^{[1
]}

Ye, Xiao-Qun ^{[1
]}

Sun, Sai-Jun ^{[1
]}

Zheng, Wen-Jun ^{[1
]}

Zhang, Run-Ju ^{[1
,2
,3
]}

Xu, Jian ^{[1
,2
,3
]}

Xing, Lan-Feng ^{[1
,2
,3
]}

Huang, He-Feng ^{[1
,2
,3
]}

机构：

[1] Zhejiang Univ, Sch Med, Womens Hosp, Hangzhou 310006, Zhejiang, Peoples R China

[2] Minist Educ China, Key Lab Reprod Genet, Beijing 310006, Peoples R China

[3] Key Lab Womens Reprod Hlth Zhejiang Prov, Hangzhou 310006, Zhejiang, Peoples R China

来源：

SCIENTIFIC REPORTS | 2014年 / 4卷

关键词：

ASSISTED REPRODUCTIVE TECHNOLOGY; AMSTERDAM PREOPERATIVE ANXIETY; EPIDERMAL-GROWTH-FACTOR; HUMAN OVARIAN TISSUE; QUALITY-OF-LIFE; NEUROPEPTIDE-Y; EUROPEAN REGISTERS; FACTOR RECEPTOR; FACTOR-ALPHA; 1ST IVF;

D O I：

10.1038/srep05028

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The study was to explore whether auricular acupressure (AA) can relieve anxiety during the period from trans-vaginal oocyte retrieval to the embryo transfer in IVF treatment and whether AA can improve the outcomes of IVF. 305 infertile patients with tubal blockage who were referred for IVF were included. The women were randomized into a control group with 102 cases, a Sham-AA group with 102 cases and an AA group with 101 cases. The anxiety levels were rated with Spielberger's State Trait Anxiety Inventory and the Amsterdam Preoperative Anxiety and Information Scale. Data of clinical pregnancy rate (CPR), implantation rate (IR) and live birth rate (LBR) were obtained. The levels of neuropeptide Y (NPY) and transforming growth factor alpha (TGF-alpha) in the follicular fluids were detected with ELISA. After treatment, in AA group, the levels of state anxiety, preoperative anxiety and need-for-information were significantly lower, whereas CPR, IR, LBR and NPY levels in the follicular fluids were markedly higher than Sham-AA group and control group. We concluded that AA could help to reduce anxiety levels associated with IVF and improves the outcomes of IVF partly through increasing the levels of NPY in the follicular fluids.

引用

页数：7

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