A convenient access to functionalized pyrazole, pyrazolyl-azole, and pyrazolo[3,4-d]pyridazine derivatives

被引：18

作者：

Dawood, Kamal M. ^{[1
]}

Farag, Ahmad M. ^{[1
]}

Abdel-Aziz, Hatem A. ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2006年 / 53卷 / 04期

关键词：

3-(2-furyl)-3-oxopropanitrile; hydrazonoyl chlorides; pyrazoles; oxadiazoles; thiadiazoles;

D O I：

10.1002/jccs.200600116

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-(2-Furyl)-3-oxopropanitrile reacts with keto and ester-hydrazonyl chlorides to afford the corresponding acetyl- and ester-pyrazole derivatives. The latter pyrazoles reacted with hydrazine and gave either the pyrazolo[3,4-d]pyridazines or pyrazolylhydrazides. Treatment of the latter hydrazides with phenylisothiocyanate and with phenylisocyanate resulted in the formation of the pyrazolylthiadiazole and pyrazolyloxadiazole derivatives, respectively.

引用

页码：873 / 880

页数：8

共 20 条

[1]

Dawood KM, 2005, J CHEM RES, P378

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