Progressive transformation of germinal centers - An uncommon cause of pediatric cervical lymphadenopathy

被引：8
作者：
Licup, Ana T.
Campisi, Paolo
Ngan, Bo-Yee
Forte, Vito
机构：
[1] Univ Toronto, Hosp Sick Children, Dept Otolaryngol Head & Neck Surg, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Hosp Sick Children, Dept Pediat Lab Med, Div Pathol, Toronto, ON M5G 1X8, Canada
来源：
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY | 2006年 / 132卷 / 07期
关键词：
D O I：
10.1001/archotol.132.7.797
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Enlarged cervical lymph nodes are a common finding in pediatric patients. The exclusion of Hodgkin lymphoma is a main indication for performing an excisional biopsy in the setting of persistently enlarged nodes or progressive involvement of other nodal groups. This case series demonstrates the close histologic characteristics of progressive transformation of germinal centers and lymphocyte-predominant Hodgkin lymphoma. Prompt surgical excision of persistently enlarged lymph nodes and close monitoring for recurrence is recommended.
引用
收藏
页码：797 / 801
页数：5
相关论文
共 11 条
[1]   DIFFERENTIAL DIAGNOSTIC FEATURES OF NODULAR L AND H HODGKINS-DISEASE, INCLUDING PROGRESSIVE TRANSFORMATION OF GERMINAL-CENTERS [J].
BURNS, BF ;
COLBY, TV ;
DORFMAN, RF .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1984, 8 (04) :253-261
[2]   Follicular hyperplasia, follicular lysis, and progressive transformation of germinal centers - A sequential spectrum of morphologic evolution in lymphoid hyperplasia [J].
Chang, CC ;
Osipov, V ;
Wheaton, S ;
Tripp, S ;
Perkins, SL .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2003, 120 (03) :322-326
[3]   PROGRESSIVE TRANSFORMATION OF GERMINAL-CENTERS WITH AND WITHOUT ASSOCIATION TO HODGKINS-DISEASE [J].
HANSMANN, ML ;
FELLBAUM, C ;
HUI, PK ;
MOUBAYED, P .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1990, 93 (02) :219-226
[4]   Progressive transformation of germinal centers: review of histopathologic and clinical features [J].
Hicks, J ;
Flaitz, C .
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2002, 65 (03) :195-202
[5]   Progressive transformation of germinal centers: A clinicopathological study of 42 Japanese patients [J].
Kojima, M ;
Nakamura, S ;
Motoori, T ;
Itoh, H ;
Shimizu, K ;
Yamane, N ;
Ohno, Y ;
Ban, S ;
Yoshida, K ;
Hoshi, K ;
Oyama, T ;
Shimano, S ;
Sugihara, S ;
Sakata, N ;
Masawa, N .
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2003, 11 (02) :101-107
[6]   Progressive transformation of germinal centers and nodular lymphocyte predominance Hodgkin's disease - A comparative immunohistochemical study [J].
Nguyen, PL ;
Ferry, JA ;
Harris, NL .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1999, 23 (01) :27-33
[7]  
OSBORNE BM, 1992, MODERN PATHOL, V5, P135
[8]   CLINICAL IMPLICATIONS OF PROGRESSIVE TRANSFORMATION OF GERMINAL-CENTERS [J].
OSBORNE, BM ;
BUTLER, JJ .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1984, 8 (10) :725-733
[9]   NODULAR PARAGRANULOMA AND PROGRESSIVELY TRANSFORMED GERMINAL-CENTERS - ULTRASTRUCTURAL AND IMMUNOHISTOLOGIC FINDINGS [J].
POPPEMA, S ;
KAISERLING, E ;
LENNERT, K .
VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY, 1979, 31 (03) :211-225
[10]   HODGKINS-DISEASE WITH LYMPHOCYTIC PREDOMINANCE, NODULAR TYPE (NODULAR PARAGRANULOMA) AND PROGRESSIVELY TRANSFORMED GERMINAL-CENTERS - CYTOHISTOLOGICAL STUDY [J].
POPPEMA, S ;
KAISERLING, E ;
LENNERT, K .
HISTOPATHOLOGY, 1979, 3 (04) :295-308
12