Highly stereospecific, palladium-catalyzed cross-coupling of alkenylsilanols

被引：153

作者：

Denmark, SE ^{[1
]}

Wehrli, D ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Roger Adams Lab, Urbana, IL 61801 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 04期

关键词：

D O I：

10.1021/ol005565e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Alkenylsilanols bearing methyl ((E)-1 and (Z)-1) or isopropyl ((E)-2 and (Z)-2)) substituents are converted to disubstituted alkenes by a palladium(0)-catalyzed cross coupling reaction with aryl or vinyl iodides in the presence of tetrabutylammonium fluoride or hydroxide, Yields and stereoselectivities are generally high, and the reaction is compatible with a wide range of functional groups.

引用

页码：565 / 568

页数：4

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