Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors

被引：27

作者：

Yasumo, H ^{[1
]}

Masuda, N ^{[1
]}

Furusawa, T ^{[1
]}

Tsukamoto, T ^{[1
]}

Sadano, H ^{[1
]}

Osumi, T ^{[1
]}

机构：

[1] Himeji Inst Technol, Dept Life Sci, Kamigori, Hyogo 6781297, Japan

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2000年 / 1490卷 / 1-2期

关键词：

peroxisome proliferator-activated receptor; two-hybrid system; protein-protein interaction; coactivator; corepressor;

D O I：

10.1016/S0167-4781(99)00244-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A protein named nuclear receptor binding factor-2 (NRBF-2) was identified by yeast two-hybrid screening, as an interaction partner of peroxisome proliferator-activated receptor a as well as several other nuclear receptors. NRBF-2 exhibited a gene activation function, when tethered to a heterologous DNA binding domain, in both mammalian cells and yeast. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：189 / 197

页数：9

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