Synthesis of furo[2,3-c]pyran-beta-D-thymidine

被引：7

作者：

Bousquie, I ^{[1
]}

Madiot, V ^{[1
]}

Florent, JC ^{[1
]}

Monneret, C ^{[1
]}

机构：

[1] INST CURIE,CNRS UMR 176,F-75231 PARIS 05,FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 15期

关键词：

D O I：

10.1016/0960-894X(96)00322-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A furo[2,2-c]pyran-beta-D-thymidine nucleoside analog was synthesized from 5'-O-TBDMS-3'-C-allyl-thymidine by 4'-C-hydroxymethylation followed by an electrophilic 6-membered ring annellation. The new bicyclonucleoside was devoid of activity against HIV. Copyright (C) 1996 Elsevier Science Ltd

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页码：1815 / 1818

页数：4

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