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Recent Advances in Fluorescent Chemosensors for Protein Kinases
被引:5
|作者:
Hu, Jun
[1
]
Li, Gao
[2
,3
]
机构:
[1] Fujian Agr & Forestry Univ, Coll Life Sci, Fuzhou 350002, Fujian, Peoples R China
[2] Minjiang Univ, Coll Mat & Chem Engn, Fujian Engn Res Ctr New Chinese Lacquer Mat, Fuzhou 350108, Fujian, Peoples R China
[3] Minjiang Univ, Inst Oceanog, Fuzhou 350108, Fujian, Peoples R China
基金:
中国国家自然科学基金;
关键词:
ATP;
chemosensors;
fluorescent;
kinase;
phosphorylation;
CELL-PENETRATING PEPTIDES;
RESONANCE ENERGY-TRANSFER;
METAL-ORGANIC FRAMEWORK;
GRAPHENE QUANTUM DOTS;
LABEL-FREE;
REAL-TIME;
PHOSPHORYLATED PEPTIDES;
COLORIMETRIC ASSAY;
PHOTOLUMINESCENT PROBES;
MOLECULAR-MECHANISMS;
D O I:
10.1002/asia.202200182
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Protein kinases are involved in almost all biological activities. The activities of different kinases reflect the normal or abnormal status of the human body. Therefore, detecting the activities of different kinases is important for disease diagnosis and drug discovery. Fluorescent probes offer opportunities for studying kinase behaviors at different times and spatial locations. In this review, we summarize different kinds of fluorescent chemosensors that have been used to detect the activities of many different kinases.
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页数:11
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