Diagnosis and Hemodynamic Assessment of Pulmonary Arterial Hypertension

被引:10
作者
Saggar, Rajan [1 ]
Saggar, Rajeev [1 ]
Aboulhosn, Jamil [1 ]
Belperio, John A. [1 ]
Zisman, David A. [1 ]
Lynch, Joseph P., III [1 ]
机构
[1] Univ Calif Los Angeles, Dept Med, Div Pulm Crit Care Med & Hospitalists, David Geffen Sch Med, 18033 Conte Ave,37-131 CHS, Los Angeles, CA 90095 USA
关键词
Pulmonary hypertension; hemodynamic; echocardiogram; diagnosis; right heart catheterization; BRAIN NATRIURETIC PEPTIDE; RIGHT ATRIAL PRESSURE; TRICUSPID REGURGITATION VELOCITY; RIGHT HEART CATHETERIZATION; RIGHT-VENTRICULAR STRUCTURE; CALCIUM-CHANNEL BLOCKERS; 6-MINUTE WALK TEST; SERUM URIC-ACID; NONINVASIVE ESTIMATION; DOPPLER-ECHOCARDIOGRAPHY;
D O I
10.1055/s-0029-1233309
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Pulmonary hypertension (PH) can occur as either a primary or a secondary process, and in general, its presence increases overall morbidity and mortality. Importantly, the majority of prior studies have been in the setting of idiopathic pulmonary arterial hypertension (IPAH); thus the following discussion focuses on IPAH. Because the ma jority of available diagnostic strategies lack sensitivity and speclificity, the physician must maintain a high index of suspicion in considering PAH. This article provides an overview of the available diagnostic studies for PAH with a particular focus oil hemodynamic assessment. Novel approaches to the often delayed diagnosis of PAH are being studied and are also discussed here.
引用
收藏
页码:399 / 410
页数:12
相关论文
共 162 条
[1]   A simple method for noninvasive estimation of pulmonary vascular resistance [J].
Abbas, AE ;
Fortuin, FD ;
Schiller, NB ;
Appleton, CP ;
Moreno, CA ;
Lester, SJ .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (06) :1021-1027
[2]   Doppler-determined peak systolic tricuspid pressure gradient in persons with normal pulmonary function and tricuspid regurgitation [J].
Aessopos, A ;
Farmakis, D ;
Taktikou, H ;
Loukopoulos, D .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2000, 13 (07) :645-649
[3]   Electrocardiography to define clinical status in primary pulmonary hypertension and pulmonary arterial hypertension secondary to collagen vascular disease [J].
Ahearn, GS ;
Tapson, VF ;
Rebeiz, A ;
Greenfield, JC .
CHEST, 2002, 122 (02) :524-527
[4]   Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences [J].
Alfakih, K ;
Plein, S ;
Thiele, H ;
Jones, T ;
Ridgway, JP ;
Sivananthan, MU .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2003, 17 (03) :323-329
[5]   NONINVASIVE DETECTION OF PULMONARY-HYPERTENSION [J].
ALGEO, S ;
MORRISON, D ;
OVITT, T ;
GOLDMAN, S .
CLINICAL CARDIOLOGY, 1984, 7 (03) :148-156
[6]   Reduced exercise capacity and stress-induced pulmonary hypertension in patients with scleroderma [J].
Alkotob, M. Luay ;
Soltani, Peyman ;
Sheatt, Mohammad A. ;
Katsetos, Manny C. ;
Rothfield, Naomi ;
Hager, W. David ;
Foley, Raymond J. ;
Silverman, David I. .
CHEST, 2006, 130 (01) :176-181
[7]   N-terminal pro-B-type natriuretic peptide as an indicator of disease severity in a heterogeneous group of patients with chronic precapillary pulmonary hypertension [J].
Andreassen, Arne K. ;
Wergeland, Ragnhild ;
Simonsen, Svein ;
Geiran, Odd ;
Guevara, Cecilia ;
Ueland, Thor .
AMERICAN JOURNAL OF CARDIOLOGY, 2006, 98 (04) :525-529
[8]  
[Anonymous], 2005, Adv Pulm Hypertens J
[9]   Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease [J].
Arcasoy, SM ;
Christie, JD ;
Ferrari, VA ;
Sutton, MS ;
Zisman, DA ;
Blumenthal, NP ;
Pochettino, A ;
Kotloff, RM .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2003, 167 (05) :735-740
[10]  
ASHERSON RA, 1990, J RHEUMATOL, V17, P1292