Monoamines and cortisol as potential mediators of the relationship between exercise and depressive symptoms

被引：25

作者：

Carneiro, Lara S. F. ^{[1
]}

Mota, Maria Paula ^{[1
]}

Vieira-Coelho, Maria Augusta ^{[2
,3
]}

Alves, Rita C. ^{[4
]}

Fonseca, Antonio Manuel ^{[5
]}

Vasconcelos-Raposo, Jose ^{[6
]}

机构：

[1] Univ Tras Os Montes & Alto Douro, Ctr Res Sports Sci Hlth & Human Dev, P-5000801 Quinta Dos Prados, Vila Real, Portugal

[2] Ctr Hosp Sao Joao, Psychiat & Mental Hlth Clin, Oporto, Portugal

[3] Univ Porto, Dept Pharmacol & Therapeut, Fac Med, Oporto, Portugal

[4] Univ Porto, LAQV Dept Chem Sci, REQUIMTE, Fac Pharm, Oporto, Portugal

[5] Univ Porto, Fac Sport, Ctr Res Educ Innovat & Intervent Sport, Oporto, Portugal

[6] Univ Tras Os Montes & Alto Douro, Dept Educ & Psychol, Vila Real, Portugal

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 2017年 / 267卷 / 02期

关键词：

Depression; Women; Aerobic exercise; Catecholamines; Cortisol; BRAIN;

D O I：

10.1007/s00406-016-0719-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A randomized controlled trial was conducted to assess the effects of exercise plus pharmacotherapy on monoamine neurotransmitters (dopamine, noradrenaline, adrenaline, serotonin) and cortisol levels. A total of 26 women with clinical depression were randomly assigned to one of the two groups: aerobic exercise plus pharmacotherapy or only pharmacotherapy. The exercise program consisted of aerobic exercise, 45-50 min/session, three times/week, for 16 weeks. The biological parameters were measured before and after the exercise program. Adding exercise to pharmacotherapy had no additional effects on monoamines and cortisol plasma levels. These data are preliminary outcomes from a small sample and should be replicated.

引用

页码：117 / 121

页数：5

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