Aquaporin water channels (Nobel lecture)

被引：523
作者：
Agre, P [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 33期
关键词：
aquaporins; medicinal chemistry; membrane proteins; Nobel lecture; protein structures;
D O I：
10.1002/anie.200460804
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Water is the most important component of all organisms and is the basis of all life. That water can pass through cell membranes has long been known-but how is the selective transport of water molecules achieved without concommitent diffusion of H3O+ ions? Peter Agre received the 2003 Nobel Prize in Chemistry for the discovery and investigation of the membrane proteins responsible, namely, the aquaproteins.
引用
收藏
页码：4278 / 4290
页数：13
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