All for One and One for All: Herpesviral MicroRNAs Close in on Their Prey

被引：1

作者：

Doelken, Lars ^{[2
]}

Jonjic, Stipan ^{[1
]}

机构：

[1] Univ Rijeka, Fac Med, Dept Histol & Embryol, Rijeka 51000, Croatia

[2] Max von Pettenkofer Inst, D-80336 Munich, Germany

来源：

CELL HOST & MICROBE | 2009年 / 5卷 / 04期

关键词：

NKG2D;

D O I：

10.1016/j.chom.2009.03.009

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Herpesviruses subvert immune cell activation by inhibiting NK cell receptor (NKG2D)-activating ligands such as MICB. A human cytomegalovirus microRNA was recently shown to repress MICB expression. Nachmani et al. (2009) extend this finding to two other human herpesviruses, providing evidence for a conserved functional role of viral microRNAs despite no sequence conservation among them.

引用

页码：315 / 317

页数：3

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