Micro-FTIR imaging spectroscopy of calcified atheromatous carotid plaques. Part IV

被引:4
作者
Alo, Francesco [3 ]
Conti, Carla [1 ]
Ferraris, Paolo [1 ]
Giorgini, Elisabetta [1 ]
Rubini, Corrado [2 ]
Sabbatini, Simona [1 ]
Tosi, Giorgio [1 ]
机构
[1] Univ Politecn Marche, Dipartimento Sci & Tecnol Chimiche, Fac Ingn, I-60131 Ancona, Italy
[2] Univ Politecn Marche, Dipartimento Neurosci, I-60131 Ancona, Italy
[3] Univ Politecn Marche, Dipartimento Patol Mol & Terapie Innovat, I-60131 Ancona, Italy
关键词
FTIR microspectroscopy; Imaging; Atherosclerosis; Gruel; Ceroid; Calcification; TRANSFORM INFRARED FTIR; BIOMEDICAL APPLICATIONS; IR MICROSPECTROSCOPY; RAMAN-SPECTROSCOPY; HYDROXYAPATITE; CALCIFICATION; DISEASE; TISSUES; ZONE;
D O I
10.1016/j.molstruc.2009.01.034
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Micro-imaging infrared spectroscopy has been performed on atheromatous plaques in order to localize and characterize substances responsible for the cytotoxic effects that prevent macrophages clearance of lipiclic and calcified materials. In plaques with different graded atherosclerotic lesions. infrared determinations allowed to visualize gruel and ceroid toxic components and variously calcified zones. Compare correlations let to visualize the progression of the lesion on going from the lumen to the outer media of the plaque. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:58 / 63
页数:6
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