Syntheses of 4-(1-alkynyl)-2(5H)-furanones and coumarins via the palladium catalyzed cross-coupling reactions of potassium alkynyltrifluoroborates

被引：34
作者：
Kabalka, GW [1 ]
Dong, G
Venkataiah, B
机构：
[1] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA
[2] Univ Tennessee, Dept Radiol, Knoxville, TN 37996 USA
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 26期
关键词：
beta-tetronic acid bromide; 4-bromocoumarin; potassium alkynlytrifluoroborates; palladium catalyzed; cross-coupling;
D O I：
10.1016/j.tetlet.2004.04.150
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of 4-(1-alkynyl)-2(5H)-furanones has been developed utilizing a palladium catalyzed coupling reaction of beta-tetronic acid bromide with potassium alkynyltrifluoroborates in the absence of base. 4-Alkynylcoumarins were also synthesized using this method. The reactions are straightforward and the yields are excellent. (C) 2004 Elsevier Ltd. All rights reserved.
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收藏
页码：5139 / 5141
页数：3
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