Semiconducting Polymer Dots Doped with Europium Complexes Showing Ultranarrow Emission and Long Luminescence Lifetime for Time-Gated Cellular Imaging

被引:89
作者
Sun, Wei [1 ]
Yu, Jiangbo [1 ]
Deng, Ruiping [2 ]
Rong, Yu [1 ]
Fujimoto, Bryant [1 ]
Wu, Changfeng [3 ]
Zhang, Hongjie [2 ]
Chiu, Daniel T. [1 ]
机构
[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA
[2] Chinese Acad Sci, State Key Lab Rare Earth Resource Utilizat, Changchun Inst Appl Chem, Changchun 130022, Peoples R China
[3] Jilin Univ, State Key Lab Integrated Optoelect, Coll Elect Sci & Engn, Changchun 130012, Jilin, Peoples R China
基金
美国国家卫生研究院; 中国国家自然科学基金;
关键词
europium; fluorescence; imaging agents; polymer dots; NANOPARTICLES; FLUORESCENCE; BRIGHTNESS; TRACKING; LIGANDS;
D O I
10.1002/anie.201304822
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Bright dots: Semiconducting polymer dots (Pdots) doped with europium complexes possess line-like fluorescence emission, high quantum yield, and long fluorescence lifetime. The Pdots successfully labeled receptors on cells. The long fluorescence lifetime of the Pdots was used to distinguish them from other red fluorescence emitting nanoparticles, and improve the signal-to-noise ratio for time-gated cellular imaging. PVK=poly(9-vinylcarbazole). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:11294 / 11297
页数:4
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