Are there different mechanisms of synchronization in the course of spike-wave discharges (SWDs) burst development in WAG/Rij rats?

被引：0
作者：
Godlevsky, Leonid S.
Vostrov, Georgy N.
Kobolev, Evgeny V.
van Luijtelaar, E. L. J. M.
Coenen, A. M. L.
Iorhachova, Mariana N.
Pereverzev, Vladimir A.
Smirnov, Igor V.
机构：
[1] Odessa State Med Univ, UA-65026 Odessa, Ukraine
[2] Natl Polytech Univ, Odessa, Ukraine
[3] Radboud Univ Nijmegen, Nijmegen, Netherlands
来源：
ACTA NEUROBIOLOGIAE EXPERIMENTALIS | 2006年 / 66卷 / 03期
关键词：
absence epilepsy; WAG/Rij genetic epilepsy; spike-wave discharges; neocortex; paleocerebellum; ECoG analysis; pair linear correlation;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
In WAG/Rij rats the pair linear correlation r was calculated for bipolar recordings in fronto-temporal, fronto-occipital and occipito-temporal zones of both hemispheres as well as in paleocerebellar cortex (culmen). It was shown that development of SWD bursts resulted in interhemispheric decreases of correlation between the right occipito-temporal cortical region on one side, and left fronto-temporal on the contralateral side. Towards the end of SWD, we found an increased interhemispheric correlation between left fronto-temporal and right fronto-occipital cortical zones, as well as, between both fronto-temporal zones. Paleocerebellum correlates at a weak to moderate level during different periods of SWD burst generation.
引用
收藏
页码：189 / 194
页数：6
相关论文
共 11 条
[1]  
[Anonymous], CENTRAL NERVOUS SYST
[2]   GENETIC MODELS OF ABSENCE EPILEPSY, WITH EMPHASIS ON THE WAG RIJ STRAIN OF RATS [J].
COENEN, AML ;
DRINKENBURG, WHIM ;
INOUE, M ;
VANLUIJTELAAR, ELJM .
EPILEPSY RESEARCH, 1992, 12 (02) :75-86
[3]   NEURONAL ACTIVITIES UNDERLYING THE ELECTROENCEPHALOGRAM AND EVOKED-POTENTIALS OF SLEEPING AND WAKING - IMPLICATIONS FOR INFORMATION-PROCESSING [J].
COENEN, AML .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 1995, 19 (03) :447-463
[4]   ABERRANT TRANSIENTS IN THE EEG OF EPILEPTIC RATS - A SPECTRAL ANALYTICAL APPROACH [J].
DRINKENBURG, WHIM ;
VANLUIJTELAAR, ELJM ;
VANSCHAIJK, WJ ;
COENEN, AML .
PHYSIOLOGY & BEHAVIOR, 1993, 54 (04) :779-783
[5]   Causes and consequences of pathogenic processes in evolution: implications from experimental epilepsy in animals [J].
Godlevsky, LS ;
van Luijtelaar, G ;
Shandra, AA ;
Coenen, AML .
MEDICAL HYPOTHESES, 2002, 58 (03) :237-243
[6]   CEREBELLAR NEURONAL-ACTIVITY CORRELATES WITH SPIKE AND WAVE EEG PATTERNS IN THE RAT [J].
KANDEL, A ;
BUZSAKI, G .
EPILEPSY RESEARCH, 1993, 16 (01) :1-9
[7]   Cortical-area specific block of genetically determined absence seizures by ethosuximide [J].
Manning, JPA ;
Richards, DA ;
Leresche, N ;
Crunelli, V ;
Bowery, NG .
NEUROSCIENCE, 2004, 123 (01) :5-9
[8]  
MEEREN HKM, 2004, ACHIEVEMENTS PHYSL S, V35, P3
[9]   Electrophysiological and pharmacological characteristics of two types of spike-wave discharges in WAG/Rij rats [J].
Midzianovskaia, IS ;
Kuznetsova, GD ;
Coenen, AML ;
Spiridonov, AM ;
van Luijtelaar, ELJM .
BRAIN RESEARCH, 2001, 911 (01) :62-70
[10]  
Paxinos G, 1998, RAT BRAIN IN STEREOTAXIC COORDINATES, FOURTH ED., pix
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